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Invitrogen
OX40 Monoclonal Antibody (443318), APC
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FIGURE: 1 / 1
OX40 Antibody (MA5-23591) in Flow
Product Details
MA5-23591
Species Reactivity
Host/Isotype
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Type
Clone
Immunogen
Conjugate
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RRID
Product Specific Information
In Western blots, no cross-reactivity with recombinant human (rh) 4-1BB, rhBAFF R, rhCD27, rhCD30, rhCD40, rhDR3, rhDR6, rhEDAR, rhFAS, rhGITR, rhHVEM, rhLT beta R, rhNGF R, rhRANK, rhRELT, rhTAJ, rhTNF RI, rhTNF RII, rhTRAIL, rhTRAIL R4, rhTRAIL R3, rhTWEAK R, or rhXEDAR is observed.
Target Information
OX40 is a protein receptor found on the surface of T cells, a type of white blood cell that plays a crucial role in the immune system. When activated, OX40 promotes the proliferation and survival of T cells, leading to a stronger immune response against cancer cells and infectious agents. OX40 agonists, which are drugs that activate OX40, have shown promising results in preclinical and clinical studies as a potential immunotherapy for cancer. They can enhance the efficacy of other cancer treatments such as chemotherapy and checkpoint inhibitors, and may also have applications in autoimmune diseases and allergies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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References (0)
Bioinformatics
Protein Aliases: ACT35 antigen; ATC35 antigen; CD134; CD134 antigen; lymphoid activation antigene ACT35; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1 receptor; Tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily, member 4
Gene Aliases: ACT35; CD134; IMD16; OX40; TNFRSF4; TXGP1L
UniProt ID: (Human) P43489
Entrez Gene ID: (Human) 7293
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