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Invitrogen
OPRK1 Polyclonal Antibody
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Product Details
PA5-33861
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Marmoset, Bat, Dog, Bovine, Hamster, Panda, Horse, Rabbit, Guinea pig (94%).
Target Information
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: K-OR-1; kappa opioid receptor; Kappa-type opioid receptor; KOPR1; KOR-1; Opiate receptor, kappa-1; opioid receptor, kappa 1; Ork1
Gene Aliases: K-OR-1; KOR; KOR-1; OPRK; OPRK1; Ror-d
UniProt ID: (Human) P41145, (Rat) P34975
Entrez Gene ID: (Human) 4986, (Rat) 29335
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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