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Alomone Labs, LTD
Noradrenaline Transporter (NET) (extracellular) Polyclonal Antibody
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FIGURE: 1 / 3
Noradrenaline Transporter (NET) (extracellular) Antibody (AMT-002-200UL) in ICC/IF
Product Details
AMT-002-200UL
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Norepinephrine Transporter [NET, or noradrenaline transporter (NAT)] is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression. Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: NaCl-dependent norepinephrine transporter; NE transporter; NET; neurotransmitter transporter, noradrenal; noradrenaline; Norepinephrine transporter; Sodium-dependent noradrenaline transporter; solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2; Solute carrier family 6 member 2; transmembrane region 4..26 transmembrane region 55..77 transmembrane region 105..123 transmembrane region 136..157
Gene Aliases: NE-T; NET; Slc6a2; Slc6a5
UniProt ID: (Mouse) O55192
Entrez Gene ID: (Rat) 83511, (Mouse) 20538
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