Invitrogen

Neuropilin 2 Polyclonal Antibody

Name: Neuropilin 2 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-120823

View all (19) Neuropilin 2 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (3)

Neuropilin 2 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 3

Neuropilin 2 Antibody (PA5-120823) in ICC/IF

Immunofluorescence analysis of Neuropilin 2 in NIH/3T3 cells. Samples were incubated with Neuropilin 2 Polyclonal antibody (Product # PA5-120823) using a dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.

Neuropilin 2 Antibody in Western Blot (WB)

Product Image Gallery

Immunogen image

Immunogen Image Neuropilin 2 Polyclonal Antibody

Product Details

PA5-120823

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

Immunocytochemistry (ICC/IF)

1:50-1:200

ELISA (ELISA)

1 µg/mL

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 21-219 of human NRP2 (NP_9577181)

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.40 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2914395

Product Specific Information

Positive test controls include: Mouse brain, Rat brain. The target is usually found in the following locations: Membrane, Secreted, Single-pass type I membrane protein.

Immunogen sequence: RGQPDPPCGG RLNSKDAGYI TSPGYPQDYP SHQNCEWIVY APEPNQKIVL NFNPHFEIEK HDCKYDFIEI RDGDSESADL LGKHCGNIAP PTIISSGSML YIKFTSDYAR QGAGFSLRYE IFKTGSEDCS KNFTSPNGTI ESPGFPEKYP HNLDCTFTIL AKPKMEIILQ FLIFDLEHDP LQVGEGDCKY DWLDIWDGI

Target Information

This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C) and SEMA3F protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F), and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Neuropilin-2; neuropilin-2a(17); neuropilin-2a(22); neuropilin-2b(0); receptor for VEGF165 and semaphorins class3; Vascular endothelial cell growth factor 165 receptor 2

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Gene Aliases: 1110048P06Rik; Np-2; NP2; Npn-2; NPN2; NRP2; PRO2714; VEGF165R2

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UniProt ID: (Human) O60462, (Mouse) O35375, (Rat) O35276

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Entrez Gene ID: (Human) 8828, (Mouse) 18187, (Rat) 81527

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Function(s)

receptor activity vascular endothelial growth factor-activated receptor activity heparin binding semaphorin receptor activity growth factor binding cytokine binding metal ion binding protein binding

Process(es)

angiogenesis positive regulation of endothelial cell proliferation cell adhesion axon guidance positive regulation of endothelial cell migration nerve development vascular endothelial growth factor signaling pathway vascular endothelial growth factor receptor signaling pathway axon extension involved in axon guidance sympathetic ganglion development sympathetic neuron projection extension sympathetic neuron projection guidance semaphorin-plexin signaling pathway involved in neuron projection guidance neural crest cell migration neuron migration multicellular organism development nervous system development heart development facial nerve structural organization vestibulocochlear nerve structural organization gonadotrophin-releasing hormone neuronal migration to the hypothalamus cell differentiation ventral trunk neural crest cell migration negative chemotaxis trigeminal ganglion development ganglion morphogenesis semaphorin-plexin signaling pathway sensory neuron axon guidance neural crest cell migration involved in autonomic nervous system development facioacoustic ganglion development

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Neuropilin 2 Polyclonal Antibody

Neuropilin 2 Antibody (PA5-120823) in ICC/IF

Product Details

PA5-120823

Western Blot (WB)

Immunocytochemistry (ICC/IF)

ELISA (ELISA)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

References (0)

Bioinformatics

Performance Guarantee

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