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Proteintech
NRF1/nuclear respiratory factor 1 Polyclonal Antibody
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Product Details
12482-1-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: LKYSTGRGK PGWGKESCKP IWWPEDIPWA NVRSDVRTEE QKQRVSWTQA LRTIVKNCYK QHGREDLLYA FEDQQTQTQA TATHSIAHLV PSQTVVQTFS NPDGTVSLIQ VGTGATVATL ADASELPTTV TVAQVNYSAV ADGEVEQNWA TLQGGEMTIQ TTQASEATQA VASLAEAAVA ASQEMQQGAT VTMALNSEAA AHAVATLAEA TLQGGGQIVL SGETAAAVGA LTGVQDANGL FMADRAGRKW ILTDKATGLV QIPVSMYQTV VTSLAQGNGP VQVAMAPVTT RISDSAVTMD GQAVEVVTLE Q (213-522 aa encoded by BC016925)
Target Information
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Alpha palindromic-binding protein; Alpha-pal; EWG; NRF-1; Nuclear respiratory factor 1; nuclear respiratory factor-1
Gene Aliases: ALPHA-PAL; C87038; D6Ertd415e; Nfe2l1_retired; NRF1
UniProt ID: (Human) Q16656, (Mouse) Q9WU00
Entrez Gene ID: (Human) 4899, (Rat) 312195, (Mouse) 18181
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