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  • NPR3 Antibodies

OriGene

NPR3 Monoclonal Antibody (OTI11A6), TrueMAB™

View all (37) NPR3 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite NPR3 Monoclonal Antibody (OTI11A6), TrueMAB™

  • Antibody Testing Data (10)
NPR3 Antibody in Immunocytochemistry (ICC/IF)
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NPR3 Antibody in Immunocytochemistry (ICC/IF)
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NPR3 Antibody (TA501076) in ICC/IF

Anti-NPR3 mouse monoclonal antibody (TA501076) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NPR3(RC219453). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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NPR3 Antibody in Immunocytochemistry (ICC/IF)
NPR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NPR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NPR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NPR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NPR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NPR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NPR3 Antibody in Western Blot (WB)
NPR3 Antibody in Western Blot (WB)
NPR3 Antibody in Flow Cytometry (Flow)
NPR3 Monoclonal Antibody (OTI11A6), TrueMAB™

Product Details

TA501076

Applications
Tested Dilution
Publications

Western Blot (WB)

1:200-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50
-

Immunocytochemistry (ICC/IF)

1:100
-

Flow Cytometry (Flow)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

OTI11A6

Immunogen

Full length human recombinant protein of human NPR3 produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.83 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: A NPR-C; ANP-C; Atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide receptor 3; Atrial natriuretic peptide receptor type C; atrionatriuretic peptide receptor C; guanylate cyclase C; natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)

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Gene Aliases: ANP-C; ANPR-C; ANPRC; C5orf23; GUCY2B; NPR-C; NPR3; NPRC

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UniProt ID: (Human) P17342

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Entrez Gene ID: (Human) 4883

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Function(s)
adenylate cyclase activity G-protein coupled peptide receptor activity natriuretic peptide receptor activity peptide hormone binding hormone binding protein homodimerization activity
Process(es)
skeletal system development osteoclast proliferation cAMP biosynthetic process adenylate cyclase-activating G-protein coupled receptor signaling pathway adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway phospholipase C-activating G-protein coupled receptor signaling pathway regulation of blood pressure cyclic nucleotide biosynthetic process cAMP-mediated signaling pancreatic juice secretion regulation of osteoblast proliferation positive regulation of urine volume phosphatidylinositol-mediated signaling negative regulation of smooth muscle cell proliferation positive regulation of nitric-oxide synthase activity
It has to be done as per old AB suggested Products section.
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