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  • NME5 Antibodies

Proteintech

NME5 Polyclonal Antibody

4 References
View all (12) NME5 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite NME5 Polyclonal Antibody

  • Antibody Testing Data (6)
NME5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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NME5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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NME5 Antibody (12923-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human prostate using 12923-1-AP (NME5 antibody) at dilution of 1:100 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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NME5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NME5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NME5 Antibody in Western Blot (WB)
NME5 Antibody in Western Blot (WB)
NME5 Antibody in Western Blot (WB)
NME5 Antibody in Immunoprecipitation (IP)
NME5 Polyclonal Antibody

Product Details

12923-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2400
View 2 publications 2 publications

Immunohistochemistry (IHC)

-
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

-
View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NME5 Fusion Protein Ag3610 (1-212 aa encoded by BC026182)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.37 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MEISMPPPQ IYVEKTLAII KPDIVDKEEE IQDIILRSGF TIVQRRKLRL SPEQCSNFYV EKYGKMFFPN LTAYMSSGPL VAMILARHKA ISYWLELLGP NNSLVAKETH PDSLRAIYGT DDLRNALHGS NDFAAAEREI RFMFPEVIVE PIPIGQAAKD YLNLHIMPTL LEGLTELCKQ KPADPLIWLA DWLLKNNPNK PKLCHHPIVE EPY (1-212 aa encoded by BC026182)

Target Information

Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 3'-5' exonuclease NME5; expressed in non-metastatic cells 5; Inhibitor of p53-induced apoptosis-beta; IPIA-beta; NDK-H 5; NDP kinase homolog 5; nm23-H5; nm23-M5; NME/NM23 family member 5; non-metastatic cells 5 protein expressed in; non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase); Nucleoside diphosphate kinase homolog 5; radial spoke 23 homolog; Rsph23; Testis-specific nm23 homolog

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Gene Aliases: 1700019D05Rik; NM23-H5; Nm23-M5; NM23H5; NME5; RSPH23

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UniProt ID: (Human) P56597, (Mouse) Q99MH5

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Entrez Gene ID: (Human) 8382, (Mouse) 75533, (Rat) 688903

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Function(s)
nucleoside diphosphate kinase activity protein binding molecular_function ATP binding
Process(es)
epithelial cilium movement nucleoside diphosphate phosphorylation GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process spermatogenesis spermatid development nucleoside metabolic process ventricular system development cilium assembly negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway response to reactive oxygen species multicellular organism development cell differentiation spermatid differentiation
It has to be done as per old AB suggested Products section.
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