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NeoBiotechnologies

NKX2.2 (Neuroendocrine and Ewing's Sarcoma Marker) Monoclonal Antibody (NX2/1524)

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite NKX2.2 (Neuroendocrine and Ewing's Sarcoma Marker) Monoclonal Antibody (NX2/1524)

  • Antibody Testing Data (4)
NKX2.2 (Neuroendocrine and Ewing's Sarcoma Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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NKX2.2 (Neuroendocrine and Ewing's Sarcoma Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 4

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NKX2.2 (Neuroendocrine and Ewing's Sarcoma Marker) Antibody (4821-MSM4-P0) in IHC (P)

Formalin-fixed, paraffin-embedded human Ewings Sarcoma stained with NKX2.2 Mouse Monoclonal Antibody (NX2/1524). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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NKX2.2 (Neuroendocrine and Ewing's Sarcoma Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NKX2.2 (Neuroendocrine and Ewing's Sarcoma Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
NKX2.2 (Neuroendocrine and Ewing's Sarcoma Marker) Antibody in Peptide array (ARRAY)
NKX2.2 (Neuroendocrine and Ewing's Sarcoma Marker) Antibody in SDS-PAGE (SDS-PAGE)
NKX2.2 (Neuroendocrine and Ewing's Sarcoma Marker) Monoclonal Antibody (NX2/1524)

Product Details

4821-MSM4-P0

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL
-

Immunocytochemistry (ICC/IF)

1-2 µg/mL
-

Flow Cytometry (Flow)

1-2 µg/10^6 cells
-

Peptide Array (Array)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

NX2/1524

Immunogen

Recombinant fragment (around aa1-119) of human NKX2.2 protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4°C, do not freeze

Shipping conditions

Wet ice

Target Information

The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Homeobox protein NK-2 homolog B; Homeobox protein Nkx-2.2; NK2 transcription factor related, locus 2; NK2 transcription factor-like protein B; Nkx2.2

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Gene Aliases: NKX2-2; NKX2.2; NKX2B

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UniProt ID: (Human) O95096

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Entrez Gene ID: (Human) 4821

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Function(s)
core promoter proximal region DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity transcription factor binding sequence-specific DNA binding
Process(es)
type B pancreatic cell development pancreatic A cell fate commitment type B pancreatic cell fate commitment pancreatic PP cell fate commitment transcription, DNA-templated smoothened signaling pathway brain development response to glucose oligodendrocyte development spinal cord motor neuron differentiation spinal cord oligodendrocyte cell fate specification optic nerve development endocrine pancreas development response to progesterone negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of transcription from RNA polymerase II promoter digestive tract development neuron fate specification astrocyte differentiation positive regulation of oligodendrocyte differentiation positive regulation of sequence-specific DNA binding transcription factor activity ventral spinal cord interneuron fate determination
It has to be done as per old AB suggested Products section.
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