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OriGene
NEUROG1 Monoclonal Antibody (OTI9A8), TrueMAB™
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Product Details
CF500308
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Storage conditions
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Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
Neurogenin 1 is a basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: bHLHa6; Class A basic helix-loop-helix protein 6; NeuroD3; Neurogenic basic-helix-loop-helix protein; neurogenic differentiation 3; Neurogenic differentiation factor 3; Neurogenin-1; NGN-1
Gene Aliases: AKA; BHLHA6; Math4C; NEUROD3; NEUROG1; NGN; NGN1
UniProt ID: (Human) Q92886
Entrez Gene ID: (Human) 4762
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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