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Proteintech
NDE1 Polyclonal Antibody
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Product Details
10233-1-AP
Species Reactivity
Published species
Host/Isotype
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Type
Immunogen
Conjugate
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Product Specific Information
This antibody is a rabbit polyclonal antibody raised against a peptide mapping within human NDE1.
Immunogen sequence: EGSREYEAE LETQLQQIET RNRDLLSENN RLRMELETIK EKFEVQHSEG YRQISALEDD LAQTKAIKDQ LQKYIRELEQ ANDDLERAKR ATIMSLEDFE QRLNQAIERN AFLESELDEK ENLLESVQRL KDEARDLRQE LAVQQKQEKP RTPMPSSVEA ERTDTAVQAT GSVPSTPIAH RGPSSSLNTP GSFRRGLDDS TGGTPLTPAA RISALNIVGD LLRKVGALES KLASCRNLVY DQS (41-282 aa encoded by BC001421)
Target Information
NDE1 is s a member of the nuclear distribution E (NudE) family of proteins. It is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. NDE1 protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations to the gene lead to Lissencephaly 4 (LIS4) and Microhydranencephaly (MHAC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: LIS1-interacting protein NUDE1; LIS1-interacting protein NUDE1, rat homolog; nuclear distribution gene E homolog 1; Nuclear distribution protein nudE homolog 1; NudE; nudE nuclear distribution E homolog 1; nudE nuclear distribution gene E homolog 1; rNudE
Gene Aliases: 2810027M15Rik; AU042936; AW822251; HOM-TES-87; LIS4; MHAC; mNudE; NDE; NDE1; NUDE; NUDE1
UniProt ID: (Human) Q9NXR1, (Rat) Q9ES39, (Mouse) Q9CZA6
Entrez Gene ID: (Human) 54820, (Rat) 83836, (Mouse) 67203
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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