NeoBiotechnologies

Myogenin/Myf-4 (Skeletal Muscle Marker) Monoclonal Antibody (SPM144)

View all (36) Myogenin antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

4656-MSM2X-P1ABX

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL
-
Product Specifications

Species Reactivity

Cat, Human, Mouse, Pig, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

SPM144

Immunogen

Human myogenin recombinant protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Target Information

Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix proteins. It is essential for the development of functional skeletal muscle.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: bHLHc3; Class C basic helix-loop-helix protein 3; Myf-4; MYOD1-related protein; Myogenic factor 4; Myogenic factor-4; Myogenin

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Gene Aliases: BHLHC3; myf-4; MYF4; myo; MYOG

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UniProt ID: (Pig) P49812, (Human) P15173, (Mouse) P12979, (Rat) P20428

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Entrez Gene ID: (Pig) 497618, (Human) 4656, (Mouse) 17928, (Rat) 29148

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Function(s)
RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding core promoter binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity E-box binding core promoter proximal region sequence-specific DNA binding DNA binding protein dimerization activity molecular_function
Process(es)
ossification transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter cell cycle multicellular organism development muscle organ development skeletal muscle tissue development negative regulation of cell proliferation positive regulation of myotube differentiation positive regulation of muscle atrophy regulation of skeletal muscle satellite cell proliferation response to muscle activity involved in regulation of muscle adaptation response to electrical stimulus involved in regulation of muscle adaptation striated muscle atrophy response to denervation involved in regulation of muscle adaptation myotube differentiation cell differentiation skeletal muscle cell differentiation mRNA transcription from RNA polymerase II promoter histone H3 acetylation histone H4 acetylation positive regulation of myoblast differentiation negative regulation of glycolytic process positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter skeletal muscle fiber development positive regulation of skeletal muscle fiber development positive regulation of cell cycle arrest cellular response to lithium ion cellular response to growth factor stimulus cellular response to estradiol stimulus regulation of myoblast fusion positive regulation of myoblast fusion positive regulation of oxidative phosphorylation response to gravity skeletal muscle atrophy response to muscle activity skeletal muscle tissue regeneration myoblast differentiation cellular response to magnetism cellular response to retinoic acid muscle cell fate commitment positive regulation of muscle cell differentiation
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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