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  • Primary Antibodies ›
  • MTR Antibodies

Invitrogen

MTR Polyclonal Antibody

View all (7) MTR antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite MTR Polyclonal Antibody

  • Antibody Testing Data (2)
MTR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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MTR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 2

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MTR Antibody (PA5-115599) in IHC (P)

Immunohistochemistry analysis of MTR in mouse kidney tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115599) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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MTR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
MTR Antibody in Western Blot (WB)
MTR Polyclonal Antibody

Product Details

PA5-115599

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human MTR(Accession Q99707), corresponding to amino acid residues M267-V317.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2900234

Product Specific Information

Antibody detects endogenous levels of total MTR.

Target Information

MTR encodes the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 5-methyltetrahydrofolate--homocysteine methyltransferase; 5-methyltetrahydrofolate-homocysteine methyltransferase 1; Cobalamin-dependent methionine synthase; FLJ33168; FLJ43216; FLJ45386; Methionine synthase; MS; Vitamin-B12 dependent methionine synthase

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Gene Aliases: AI894170; cblG; D830038K18Rik; HMAG; methioninesynthase; MS; MTR

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UniProt ID: (Human) Q99707, (Rat) Q9Z2Q4, (Mouse) A6H5Y3

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Entrez Gene ID: (Human) 4548, (Rat) 81522, (Mouse) 238505

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Function(s)
protein binding zinc ion binding methionine synthase activity S-adenosylmethionine-homocysteine S-methyltransferase activity cobalamin binding folic acid binding methyltransferase activity amino acid binding transferase activity metal ion binding
Process(es)
sulfur amino acid metabolic process nervous system development methionine biosynthetic process cobalamin metabolic process axon regeneration methylation pteridine-containing compound metabolic process response to axon injury cellular response to nitric oxide protein methylation methionine metabolic process tetrahydrofolate metabolic process homocysteine metabolic process cellular response to methionine cellular amino acid biosynthetic process cellular metabolic process
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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