Proteintech

MTHFS Polyclonal Antibody

Name: MTHFS Polyclonal Antibody
Brand: Proteintech
SKU: 13114-1-AP

View all (8) MTHFS antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (10)

MTHFS Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 10

MTHFS Antibody (13114-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human liver cancer using 13114-1-AP (MTHFS antibody) at dilution of 1:100 (under 40x lens).

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Immunogen image

Immunogen Image MTHFS Polyclonal Antibody

Product Details

13114-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MTHFS Fusion Protein Ag3781 (1-203 aa encoded by BC019921)

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.14 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAAAAVSSA KRSLRGELKQ RLRAMSAEER LRQSRVLSQK VIAHSEYQKS KRISIFLSMQ DEIETEEIIK DIFQRGKICF IPRYRFQSNH MDMVRIESPE EISLLPKTSW NIPQPGEGDV REEALSTGGL DLIFMPGLGF DKHGNRLGRG KGYYDAYLKR CLQHQEVKPY TLALAFKEQI CLQVPVNEND MKVDEVLYED SSTA (1-203 aa encoded by BC019921)

Target Information

Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 5, 10-methenyltetrahydrofolate synthetase; 5,10-methenyl-tetrahydrofolate synthetase; 5-formyltetrahydrofolate cyclo-ligase; FLJ30410; methenyl-THF synthetase; MTHFS

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Gene Aliases: 1110034I12Rik; 2310020H23Rik; AI119695; HsT19268; MTHFS

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UniProt ID: (Human) P49914, (Mouse) Q9D110

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Entrez Gene ID: (Human) 10588, (Rat) 300886, (Mouse) 107885

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Function(s)

ATP binding folic acid binding 5-formyltetrahydrofolate cyclo-ligase activity metal ion binding molecular_function protein homodimerization activity protein heterodimerization activity nucleotide binding ligase activity

Process(es)

biological_process metabolic process intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of apoptotic process tetrahydrofolate metabolic process extrinsic apoptotic signaling pathway in absence of ligand negative regulation of intrinsic apoptotic signaling pathway glutamate metabolic process folic acid-containing compound biosynthetic process formate metabolic process tetrahydrofolate interconversion folic acid metabolic process folic acid catabolic process

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MTHFS Polyclonal Antibody

MTHFS Antibody (13114-1-AP) in IHC (P)

Product Details

13114-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

References (0)

Bioinformatics

Performance Guarantee

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