Proteintech

MTERF Polyclonal Antibody

Name: MTERF Polyclonal Antibody
Brand: Proteintech
SKU: 16957-1-AP

2 References

View all (8) MTERF antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (2)

FIGURE: 1 / 2

MTERF Antibody (16957-1-AP) in WB

Jurkat cells were subjected to SDS PAGE followed by western blot with 16957-1-AP (MTERF antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

Product Image Gallery

Immunogen image

Immunogen Image MTERF Polyclonal Antibody

Product Details

16957-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MTERF Fusion Protein Ag10640 (1-399 aa encoded by BC000965)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.29 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MQSLSLGQT SISKGLNYLT IMAPGNLWHM RNNFLFGSRC WMTRFSAENI FKSVSFRLFG VKCHNTDSEP LKNEDLLKNL LTMGVDIDMA RKRQPGVFHR MITNEQDLKM FLLSKGASKE VIASIISRYP RAITRTPENL SKRWDLWRKI VTSDLEIVNI LERSPESFFR SNNNLNLENN IKFLYSVGLT RKCLCRLLTN APRTFSNSLD LNKQMVEFLQ AAGLSLGHND PTDFVRKIIF KNPFILIQST KRVKANIEFL RSTFNLNSEE LLVLICGPGA EILDLSNDYA RRSYANIKEK LFSLGCTEEE VQKFVLSYPD VIFLAEKKFN DKIDCLMEEN ISISQIIENP RVLDSSISTL KSRIKELVNA GCNLSTLNIT LLSWSKKRYE AKLKKLSRFA (1-399 aa encoded by BC000965)

Target Information

Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria.

Nature communications

Matic S,Jiang M,Nicholls TJ,Uhler JP,Dirksen-Schwanenland C,Polosa PL,Simard ML,Li X,Atanassov I,Rackham O,Filipovska A,Stewart JB,Falkenberg M,Larsson NG,Milenkovic D

Fri Mar 23 00:00:00 UTC 2018

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria.

Nature communications

Matic S,Jiang M,Nicholls TJ,Uhler JP,Dirksen-Schwanenland C,Polosa PL,Simard ML,Li X,Atanassov I,Rackham O,Filipovska A,Stewart JB,Falkenberg M,Larsson NG,Milenkovic D

Fri Mar 23 00:00:00 UTC 2018

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity.

Nature immunology

Geng J,Sun X,Wang P,Zhang S,Wang X,Wu H,Hong L,Xie C,Li X,Zhao H,Liu Q,Jiang M,Chen Q,Zhang J,Li Y,Song S,Wang HR,Zhou R,Johnson RL,Chien KY,Lin SC,Han J,Avruch J,Chen L,Zhou D

Sun Nov 01 00:00:00 UTC 2015

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity.

Nature immunology

Geng J,Sun X,Wang P,Zhang S,Wang X,Wu H,Hong L,Xie C,Li X,Zhao H,Liu Q,Jiang M,Chen Q,Zhang J,Li Y,Song S,Wang HR,Zhou R,Johnson RL,Chien KY,Lin SC,Han J,Avruch J,Chen L,Zhou D

Sun Nov 01 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: Mitochondrial transcription termination factor 1; Mitochondrial transcription termination factor 1a; mitochondrial transcription termination factor 1b; mTERF; mTERF1a; mterf1b; Transcription termination factor 1, mitochondrial; Transcription termination factor 1a, mitochondrial; transcription termination factor, mitochondrial

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Gene Aliases: 4931431L11Rik; 9230106K09Rik; MTERF; MTERF1; Mterf1a; mTERF1b

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UniProt ID: (Human) Q99551, (Rat) Q9EPI8, (Mouse) Q8CHZ9

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Entrez Gene ID: (Human) 7978, (Rat) 85261, (Mouse) 545725

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Function(s)

double-stranded DNA binding protein binding poly(A) RNA binding DNA binding

Process(es)

transcription, DNA-templated DNA-templated transcription, termination regulation of transcription, DNA-templated termination of mitochondrial transcription DNA geometric change mitochondrion organization

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MTERF Polyclonal Antibody

MTERF Antibody (16957-1-AP) in WB

Product Details

16957-1-AP

Western Blot (WB)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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