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Invitrogen
MMP13 Monoclonal Antibody (VIIIA2)
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Product Details
MA5-14238
Species Reactivity
Published species
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Conjugate
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Product Specific Information
MA5-14238 targets MMP-13 (Collagenase-3) in IHC (P) and IP applications and shows reactivity with Human, mouse, and Rabbit samples.
The MA5-14238 immunogen is human recombinant collagenase-3 protein.
Target Information
MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Collagenase; Collagenase 3; collagenase-1; Collagenase-3; Collagenase3; interstitial collagenase; matrix metallo protease; matrix metalloproteinase 13; matrix metalloproteinase 13 (collagenase 3); Matrix metalloproteinase-13; MMP; MMP-13; MMPs; Procollagenase 3
Gene Aliases: Clg; CLG3; MANDP1; MMP-13; Mmp1; MMP13
UniProt ID: (Human) P45452, (Mouse) P33435
Entrez Gene ID: (Human) 4322, (Mouse) 17386
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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