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Proteintech

MLX Polyclonal Antibody

4 References
View all (15) MLX antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite MLX Polyclonal Antibody

  • Antibody Testing Data (3)
MLX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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MLX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 3

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MLX Antibody (12042-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human prostate cancer using 12042-1-AP (MLX antibody) at dilution of 1:50 (under 10x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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MLX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
MLX Antibody in Western Blot (WB)
MLX Antibody in Western Blot (WB)
MLX Polyclonal Antibody

Product Details

12042-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

-
View 2 publications 2 publications
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MLX Fusion Protein Ag2671 (1-244 aa encoded by BC010689)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.45 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MTEPGASPE DPWVKVEYAY SDNSLDPGLF VESTRKGSVV SRANSIGSTS ASSVPNTDDE DSDYHQEAYK ESYKDRRRRA HTQAEQKRRD AIKRGYDDLQ TIVPTCQQQD FSIGSQKLSK AIVLQKTIDY IQFLHKEKKK QEEEVSTLRK DVTALKIMKV NYEQIVKAHQ DNPHEGEDQV SDQVKFNVFQ GIMDSLFQSF NASISVASFQ ELSACVFSWI EEHCKPQTLR EIVIGVLHQL KNQLY (1-244 aa encoded by BC010689)

Target Information

The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: bHLHd13; BigMax alpha; BigMax protein; Class D basic helix-loop-helix protein 13; MAX-like bHLHZIP protein; max-like factor protein; Max-like protein X; Protein BigMax; transcription factor like 4; transcription factor-like 4; Transcription factor-like protein 4

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Gene Aliases: BHLHD13; MAD7; MLX; MXD7; TCFL4

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UniProt ID: (Human) Q9UH92, (Mouse) O08609

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Entrez Gene ID: (Human) 6945, (Rat) 360631, (Mouse) 21428

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Function(s)
RNA polymerase II regulatory region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein homodimerization activity protein heterodimerization activity protein dimerization activity
Process(es)
negative regulation of transcription from RNA polymerase II promoter regulation of transcription from RNA polymerase II promoter nucleocytoplasmic transport negative regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription, DNA-templated transcription from RNA polymerase II promoter
It has to be done as per old AB suggested Products section.
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