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Invitrogen
MKL1 Polyclonal Antibody
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Product Details
PA5-68893
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
This target displays homology in the following species: Cow: 86%; Dog: 86%; Horse: 86%; Human: 79%; Mouse: 100%; Pig: 86%; Rabbit: 86%; Rat: 100%; Zebrafish: 75%
Target Information
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: basic SAP and coiled-coil domains; Basic SAP coiled-coil transcription activator; megakaryoblastic leukemia (translocation) 1 homolog; Megakaryoblastic leukemia 1 protein homolog; Megakaryocytic acute leukemia protein homolog; mixed lineage leukemia; MKL/myocardin-like protein 1; MRTF-A; Myocardin-related transcription factor A
Gene Aliases: AMKL; Bsac; Mal; Mkl1; Mrtf-A; Mrtfa
UniProt ID: (Mouse) Q8K4J6
Entrez Gene ID: (Mouse) 223701
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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