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  • MICA/MICB Antibodies

Proteintech

MICA/MICB Monoclonal Antibody (6D4), FITC Plus

View all (17) MICA/MICB antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite MICA/MICB Monoclonal Antibody (6D4), FITC Plus

  • Antibody Testing Data (2)
MICA/MICB Antibody in Flow Cytometry (Flow)
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MICA/MICB Antibody in Flow Cytometry (Flow)
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FIGURE: 1 / 2

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MICA/MICB Antibody (FITC-65161) in Flow

1X10^6 HeLa cells were surface stained with 5 µL FITC Plus Anti-Human MICA/MICB (FITC-65161, Clone:6D4) or Mouse IgG2a Isotype Control. Cells were not fixed. Live cells were gated. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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MICA/MICB Antibody in Flow Cytometry (Flow)
MICA/MICB Antibody in Flow Cytometry (Flow)

Product Details

FITC-65161

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

6D4

Immunogen

Transfected C1R cells expressing MICA

Conjugate

FITC Plus FITC Plus FITC Plus
  • APC 
  • Biotin 
  • Cardinal Red
  • CoraLite Plus 488
  • CoraLite Plus 647
  • CoraLite Plus 670
  • CoraLitePlus 555
  • PE 
  • Request custom conjugation

Excitation/Emission Max

495/524 nm

Form

Liquid

Purification

Size-exclusion chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

4°C, store in dark

Shipping conditions

Wet ice

Target Information

MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: HLA class I antigen; MHC class I chain-related protein A; MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I polypeptide-related sequence A; MHC class I polypeptide-related sequence B; MHC class I related sequence A; MHC class I-like molecule PERB11.2-IMX; MIC-A; MIC-B; MICA; MICB; sMICA; sMICB; soluble MICA; soluble MICB; stress inducible class I homolog; truncated MHC class I polypeptide-related sequence A

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Gene Aliases: MIC-A; MICA; MICB; PERB11.1; PERB11.2

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UniProt ID: (Human) Q9UE11, (Human) Q29980

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Entrez Gene ID: (Human) 100507436, (Human) 4277

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Function(s)
antigen binding protein binding beta-2-microglobulin binding natural killer cell lectin-like receptor binding
Process(es)
T cell mediated cytotoxicity immune response to tumor cell cellular response to DNA damage stimulus response to heat cytolysis antigen processing and presentation negative regulation of natural killer cell activation natural killer cell mediated cytotoxicity defense response to bacterium negative regulation of natural killer cell mediated cytotoxicity gamma-delta T cell activation regulation of immune response defense response to virus immune response-activating cell surface receptor signaling pathway response to oxidative stress viral process response to retinoic acid negative regulation of defense response to virus by host
It has to be done as per old AB suggested Products section.
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