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Invitrogen
MDFI Polyclonal Antibody
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FIGURE: 1 / 7
MDFI Antibody (PA5-101683) in ICC/IF
Product Details
PA5-101683
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Concentration
Purification
Storage buffer
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RRID
Product Specific Information
Antibody detects endogenous levels of total MDFI.
Target Information
MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: inhibitor of MyoD family a; MyoD family inhibitor; Myogenic repressor I-mf
Gene Aliases: I-MF; I-mfa; MDFI; RGD1560271
UniProt ID: (Human) Q99750, (Mouse) P70331
Entrez Gene ID: (Human) 4188, (Mouse) 17240, (Rat) 501097
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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