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NeoBiotechnologies

MCM2 (Proliferation Marker) Recombinant Rabbit Monoclonal Antibody (MCM2/8006R)

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Datasheet
Protocols
Questions & Answers

Cite MCM2 (Proliferation Marker) Recombinant Rabbit Monoclonal Antibody (MCM2/8006R)

MCM2 (Proliferation Marker) Recombinant Rabbit Monoclonal Antibody (MCM2/8006R)
  • Antibody Testing Data (1)
MCM2 (Proliferation Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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MCM2 (Proliferation Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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MCM2 (Proliferation Marker) Antibody (4171-RBM5-P1ABX) in IHC (P)

Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with MCM2 Recombinant Rabbit Monoclonal Antibody (MCM2/8006R). Inset: PBS instead of primary antibody, secondary only control. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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MCM2 (Proliferation Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

4171-RBM5-P1ABX

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

MCM2/8006R

Immunogen

Recombinant fragment (aa 1-200) of human MCM2 protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. MCM2 has been mapped to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: cell devision cycle-like 1; cyclin-like 1; DNA replication licensing factor MCM2; MGC10606; minichromosome maintenance deficient 2 (mitotin); Minichromosome maintenance protein 2 homolog; Nuclear protein BM28

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Gene Aliases: BM28; CCNL1; cdc19; CDCL1; D3S3194; DFNA70; KIAA0030; MCM2; MITOTIN

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UniProt ID: (Human) P49736

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Entrez Gene ID: (Human) 4171

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Function(s)
DNA binding DNA helicase activity DNA replication origin binding protein binding ATP binding enzyme binding histone binding metal ion binding
Process(es)
G1/S transition of mitotic cell cycle DNA replication DNA unwinding involved in DNA replication DNA replication initiation nucleosome assembly cell cycle cellular response to interleukin-4
It has to be done as per old AB suggested Products section.
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