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  • MCCC2 Antibodies

Invitrogen

MCCC2 Polyclonal Antibody

View all (12) MCCC2 antibodies

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Datasheet
Protocols
Questions & Answers

Cite MCCC2 Polyclonal Antibody

  • Antibody Testing Data (1)
MCCC2 Antibody in Western Blot (WB)
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MCCC2 Antibody in Western Blot (WB)
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MCCC2 Antibody (PA5-96888) in WB

Western blot analysis of MCCC2 in extracts of various cell lines. Samples were incubated with MCCC2 Polyclonal antibody (Product # PA5-96888) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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MCCC2 Antibody in Western Blot (WB)
MCCC2 Polyclonal Antibody

Product Details

PA5-96888

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 284-563 of human MCCC2 (NP_0714151)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2808690

Product Specific Information

Immunogen sequence: LHLTRKVVRN LNYQKKLDVT IEPSEEPLFP ADELYGIVGA NLKRSFDVRE VIARIVDGSR FTEFKAFYGD TLVTGFARIF GYPVGIVGNN GVLFSESAKK GTHFVQLCCQ RNIPLLFLQN ITGFMVGREY EAEGIAKDGA KMVAAVACAQ VPKITLIIGG SYGAGNYGMC GRAYSPRFLY IWPNARISVM GGEQAANVLA TITKDQRARE GKQFSSADEA ALKEPIIKKF EEEGNPYYSS ARVWDDGIID PADTRLVLGL SFSAALNAPI EKTDFGIFRM; Positive Samples: HeLa, HepG2, K562, U-251MG, mouse liver, mouse kidney, mouse heart, rat brain, rat kidney, MCF7, 22Rv1, Mouse liver, Mouse kidney, Mouse heart, Rat brain; Cellular Location: Mitochondrion matrix

Target Information

COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; biotin carboxylase; MCCase subunit beta; meth; methylcrotonoyl-CoA carboxylase 2 (beta); Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; methylcrotonoyl-Coenzyme A carboxylase 2 (beta); non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase; testicular secretory protein Li 29

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Gene Aliases: 4930552N12Rik; MCCB; MCCC2

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UniProt ID: (Human) Q9HCC0, (Rat) Q5XIT9, (Mouse) Q3ULD5

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Entrez Gene ID: (Human) 64087, (Rat) 361884, (Mouse) 78038

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Function(s)
methylcrotonoyl-CoA carboxylase activity protein binding ATP binding nucleotide binding ligase activity
Process(es)
leucine catabolic process coenzyme A metabolic process biotin metabolic process branched-chain amino acid catabolic process protein heterooligomerization
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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