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Invitrogen
MC1R Monoclonal Antibody (578CT6.2.3)
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Product Details
MA5-37591
Species Reactivity
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Immunogen
Conjugate
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Target Information
MC1R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). MSH and its receptor, MC1R, are key regulators of melanogenesis. They control the relative proportions of red pheomelanin and black photoprotective eumelanin in the skin by increasing the production of eumelanin. Non-functional, truncated forms of the receptor lead to lighter coat color in animals. In contrast, constitutively active receptors lead to darker color.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: alpha melanocyte stimulating hormone receptor; MC1 receptor; MC1-R; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); Melanocortin receptor 1; Melanocyte-stimulating hormone receptor; melanotropin receptor; MSH-R
Gene Aliases: CMM5; MC1R; MSH-R; MSHR; SHEP2
UniProt ID: (Human) Q01726
Entrez Gene ID: (Human) 4157
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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