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Invitrogen

MAD2 Recombinant Rabbit Monoclonal Antibody (JU46-13)

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite MAD2 Recombinant Rabbit Monoclonal Antibody (JU46-13)

  • Antibody Testing Data (1)
MAD2 Antibody in Western Blot (WB)
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MAD2 Antibody in Western Blot (WB)
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MAD2 Antibody (MA5-34624) in WB

Western blot analysis of Mad2L1 in Positive control: Lane 1: K562, Lane 2: 293T, Lane 3: SH-SY5Y. Samples were incubated with Mad2L1 monoclonal antibody (Product # MA5-34624), at a dilution of 1:500. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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MAD2 Antibody in Western Blot (WB)
MAD2 Recombinant Rabbit Monoclonal Antibody (JU46-13)

Product Details

MA5-34624

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

JU46-13

Immunogen

Recombinant protein within Human Mad2L1 aa 69-124
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 40% glycerol, 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2848532

Product Specific Information

Positive Control: K562, 293T, SH-SY5Y.

Target Information

Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: HsMAD2; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; MAD2-like 1; MAD2-like protein 1; MadL1; Mitotic arrest deficient 2-like protein 1; mitotic arrest deficient, yeast, homolog-like 1; Mitotic spindle assembly checkpoint protein MAD2A

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Gene Aliases: HSMAD2; MAD2; MAD2L1

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UniProt ID: (Human) Q13257

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Entrez Gene ID: (Human) 4085

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Function(s)
protein binding identical protein binding protein homodimerization activity
Process(es)
mitotic sister chromatid segregation sister chromatid cohesion mitotic cell cycle checkpoint mitotic spindle assembly checkpoint anaphase-promoting complex-dependent catabolic process negative regulation of protein catabolic process protein ubiquitination involved in ubiquitin-dependent protein catabolic process negative regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process negative regulation of mitotic cell cycle cell division negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition positive regulation of mitotic cell cycle spindle assembly checkpoint negative regulation of ubiquitin protein ligase activity
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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