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Invitrogen
LMX1B Polyclonal Antibody
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FIGURE: 1 / 2
LMX1B Antibody (PA5-78395) in IHC (F)
Product Details
PA5-78395
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Purification
Storage buffer
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RRID
Product Specific Information
Positive Control: mouse skeletal muscle
Predicted Reactivity: Human (100%), Pig (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
LMX1B, LIM homeobox transcription factor 1B, belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: LIM homeo box transcription factor 1B; LIM homeobox transcription factor 1 beta; LIM homeobox transcription factor 1, beta; LIM homeobox transcription factor 1-beta; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX-1.2
Gene Aliases: LMX1.1; LMX1.2; LMX1B; NPS1
UniProt ID: (Human) O60663, (Mouse) O88609
Entrez Gene ID: (Human) 4010, (Rat) 114501, (Mouse) 16917
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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