OriGene

LHX1 Monoclonal Antibody (OTI1D5), TrueMAB™

View all (44) LIM1 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers
LHX1 Monoclonal Antibody (OTI1D5), TrueMAB™

Product Details

TA504533

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1D5

Immunogen

Human recombinant protein fragment corresponding to amino acids 100-362 of human LHX1 produced in E.coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of neural and lymphoid cells. A similar protein in mice is an essential regulator of the vertebrate head organizer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: hLim-1; Homeobox protein Lim-1; LHX-1; LIM homeobox protein 1; LIM/homeobox protein Lhx1; MGC126723; MGC138141

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Gene Aliases: LHX1; LIM-1; LIM1

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UniProt ID: (Human) P48742

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Entrez Gene ID: (Human) 3975

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Function(s)
transcription factor activity, sequence-specific DNA binding transcription corepressor activity zinc ion binding sequence-specific DNA binding
Process(es)
urogenital system development ureteric bud development branching involved in ureteric bud morphogenesis gastrulation with mouth forming second ectoderm formation endoderm formation kidney development transcription from RNA polymerase II promoter cell-cell signaling pattern specification process nervous system development motor neuron axon guidance anatomical structure morphogenesis post-embryonic development embryonic pattern specification organ morphogenesis anterior/posterior axis specification anterior/posterior pattern specification dorsal/ventral pattern formation regulation of gene expression retina layer formation ventral spinal cord development spinal cord association neuron differentiation telencephalon development cerebellum development cerebellar Purkinje cell differentiation forebrain regionalization cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation somite rostral/caudal axis specification metanephric part of ureteric bud development oviduct epithelium development uterine epithelium development nephric duct elongation horizontal cell localization positive regulation of embryonic development cellular response to fibroblast growth factor stimulus negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated anatomical structure formation involved in morphogenesis embryonic viscerocranium morphogenesis pronephros development embryonic retina morphogenesis in camera-type eye uterus development oviduct development cervix development vagina development head development epithelium development paramesonephric duct development comma-shaped body morphogenesis S-shaped body morphogenesis renal vesicle morphogenesis mesonephric duct development nephric duct morphogenesis metanephric glomerulus development metanephric comma-shaped body morphogenesis metanephric renal vesicle morphogenesis metanephric S-shaped body morphogenesis primitive streak formation positive regulation of branching involved in ureteric bud morphogenesis lateral motor column neuron migration positive regulation of gastrulation positive regulation of anterior head development positive regulation of nephron tubule epithelial cell differentiation
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