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  • LEO1 Antibodies

Invitrogen

LEO1 Polyclonal Antibody

View all (11) LEO1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite LEO1 Polyclonal Antibody

  • Antibody Testing Data (2)
LEO1 Antibody in Immunocytochemistry (ICC/IF)
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LEO1 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 2

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LEO1 Antibody (PA5-83513) in ICC/IF

Immunofluorecent analysis of LEO1 in human cell line U-251 MG using LEO1 Polyclonal Antibody (Product # PA5-83513). Staining shows localization to nucleoplasm, nucleoli fibrillar center and centrosome. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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LEO1 Antibody in Immunocytochemistry (ICC/IF)
LEO1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
LEO1 Polyclonal Antibody

Product Details

PA5-83513

Applications
Tested Dilution
Publications

Western Blot (WB)

0.04-0.4 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500
-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LEO1. Recombinant protein control fragment (Product #RP-98172).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2790666

Product Specific Information

Immunogen sequence: SGQPSNKELF GDDSEDEGAS HHSGSDNHSE RSDNRSEASE RSDHEDNDPS DVDQHSGSEA PNDDEDEGHR SDGGSHHSEA EGSEKAHSDD EKWGREDKSD QSDDEKIQNS D

Target Information

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Leo1 Paf1/RNA polymerase II complex component; Leo1, Paf1/RNA polymerase II complex component, homolog; Replicative senescence down-regulated leo1-like protein; RNA polymerase-associated protein LEO1

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Gene Aliases: LEO1; RDL

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UniProt ID: (Human) Q8WVC0

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Entrez Gene ID: (Human) 123169

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Function(s)
protein binding RNA polymerase II C-terminal domain phosphoserine binding
Process(es)
endodermal cell fate commitment transcription elongation from RNA polymerase II promoter mRNA polyadenylation histone monoubiquitination Wnt signaling pathway stem cell population maintenance positive regulation of mRNA 3'-end processing positive regulation of transcription elongation from RNA polymerase II promoter histone H2B ubiquitination negative regulation of myeloid cell differentiation positive regulation of transcription from RNA polymerase II promoter beta-catenin-TCF complex assembly
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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