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  • KISS1R Antibodies

Proteintech

KISS1R Polyclonal Antibody

5 References
View all (11) KISS1R antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite KISS1R Polyclonal Antibody

  • Antibody Testing Data (9)
KISS1R Antibody in Immunocytochemistry (ICC/IF)
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KISS1R Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 9

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KISS1R Antibody (15505-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using KISS1R antibody 15505-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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KISS1R Antibody in Immunocytochemistry (ICC/IF)
KISS1R Antibody in Immunocytochemistry (ICC/IF)
KISS1R Antibody in Immunocytochemistry (ICC/IF)
KISS1R Antibody in Immunohistochemistry (Paraffin) (IHC (P))
KISS1R Antibody in Immunohistochemistry (Paraffin) (IHC (P))
KISS1R Antibody in Western Blot (WB)
KISS1R Antibody in Western Blot (WB)
KISS1R Antibody in Western Blot (WB)
KISS1R Antibody in Flow Cytometry (Flow)

Product Details

15505-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunocytochemistry (ICC/IF)

1:10-1:100
View 1 publication 1 publication

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells
-

Not applicable (N/A)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse

Published species

Bovine

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

GCPR54 is a galanin-like G protein coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the protein suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that it appears to play a role in the onset of puberty. GPR54 has been reported in various human brain regions, placenta, pancreas, and spinal cord, and at lower levels in spleen, peripheral blood leukocytes, testis, lymph node, thymus, small intestine, stomach, lung, and kidney. The receptor is also abundant in tumor tissues. In rat, GPR54 is expressed in liver, intestine, and in the pons, midbrain, thalamus, hypothalamus, hippocampus, amygdala, cortex (including frontal), and striatum. ESTs have been isolated from normal placenta and kidney cancer libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: G protein-coupled receptor 54; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; hOT7T175; Hypogonadotropin-1; KiSS-1 receptor; KiSS-1R; Kisspeptins receptor; Metastin receptor; mOT7T175; orphan G protein-coupled receptor 54

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Gene Aliases: AXOR12; CPPB1; GPR54; HH8; HOT7T175; KiSS-1; KISS-1R; KISS1R

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UniProt ID: (Human) Q969F8, (Mouse) Q91V45

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Entrez Gene ID: (Human) 84634, (Mouse) 114229

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Function(s)
protein binding neuropeptide receptor activity neuropeptide binding signal transducer activity G-protein coupled receptor activity G-protein coupled peptide receptor activity
Process(es)
activation of MAPKK activity signal transduction G-protein coupled receptor signaling pathway neuropeptide signaling pathway chemical synaptic transmission negative regulation of cell proliferation calcium-mediated signaling negative regulation of cell migration positive regulation of hormone secretion arachidonic acid secretion positive regulation of synaptic transmission positive regulation of stress fiber assembly phospholipase C-activating G-protein coupled receptor signaling pathway
It has to be done as per old AB suggested Products section.
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