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Invitrogen
KIP2 Polyclonal Antibody
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FIGURE: 1 / 5
KIP2 Antibody (PA5-104486) in ICC/IF
Product Details
PA5-104486
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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RRID
Product Specific Information
Antibody detects endogenous levels of total CIB2.
Target Information
DNA-dependent protein kinases (DNA-PK) play a role in the repair of double-strand DNA breaks and in the process of V(D)J recombination during lymphoid development. By EST database searching for sequences homologous to the DNA-PK gene KIP/CIB and 5-prime RACE, Seki, N et al. isolated a full-length cDNA, which they designated as KIP2, from a human fetal brain cDNA library. KIP2 encodes a deduced 187-amino acid protein with a predicted molecular mass of 22 kD. The KIP2 protein shares 46%, 39%, and 30% sequence identity with the calcium-binding proteins KIP/CIB, calcineurin B and calmodulin respectively. KIP2 contains two EF-hand motifs and a helix-loop-helix motif involved in coordinating the calcium ion, indicating that KIP2 may also bind calcium. KIP2 is ubiquitously expressed in various human tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Calcium and integrin-binding family member 2; calcium binding protein Kip 2; calcium binding protein Kip2; DNA-dependent protein kinase catalytic subunit-interacting protein 2; kinase interacting protein 2; Kinase-interacting protein 2; KIP 2
Gene Aliases: 2810434I23Rik; AI449053; CIB2; DFNB48; KIP2; USH1J
UniProt ID: (Human) O75838, (Rat) Q568Z7, (Mouse) Q9Z309
Entrez Gene ID: (Human) 10518, (Rat) 300719, (Mouse) 56506
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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