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Proteintech
KIF1B Polyclonal Antibody
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Product Details
15263-1-AP
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Product Specific Information
Immunogen sequence: TSVAYVRGE ENLAGWRPRG DSLILEHQWE LEKLELLHEV EKTRHFLLLR ERLGDSIPKS LSDSLSPSLS SGTLSTSTSI SSQISTTTFE SAITPSESSG YDSGDIESLV DREKELATKC LQLLTHTFNR EFSQVHGSVS DCKLSDISPI GRDPSESSFS SATLTPSSTC PSLVDSRSNS LDQKTPEANS RASSPCPEFE QFQIVPAVET PYLARAGKNE FLNLVPDIEE IRPSSVVSKK GYLHFKEPLY SNWAKHFVVV RRPYVFIYNS DKDPVERGII NLSTAQVEYS EDQQAMVKTP NTFAVCTKHR GVLLQALNDK DMNDWLYAFN PLLAGTIRSK LSRRCPSQSK Y (230-579 aa encoded by BC001415)
Target Information
The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1B is an amino-terminal-type motor protein that is ubiquitously expressed, with the most abundant levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36. 2. Defects in axonal transport due to mutations at the KIF1B gene can underlie the human peripheral neuropathy phenotype. The mouse KIF1B gene generates an alternatively spliced transcript, which produces two isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: kinesin heavy chain member 1B; kinesin superfamily protein KIF1B; kinesin-family protein KIF1Bbeta3; Kinesin-like protein KIF1B; Klp; N-3 kinesin
Gene Aliases: A530096N05Rik; AI448212; AI506502; CMT2; CMT2A; CMT2A1; D4Mil1e; HMSNII; KIAA0591; KIAA1448; KIF1B; KIF1Bp130; KIF1Bp204; KLP; NBLST1
UniProt ID: (Human) O60333, (Rat) O88658, (Mouse) Q60575
Entrez Gene ID: (Human) 23095, (Rat) 117548, (Mouse) 16561
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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