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  • Primary Antibodies ›
  • JMJD2B Antibodies

Invitrogen

JMJD2B Monoclonal Antibody (3A6H6)

View all (21) JMJD2B antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite JMJD2B Monoclonal Antibody (3A6H6)

  • Antibody Testing Data (4)
JMJD2B Antibody in Western Blot (WB)
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JMJD2B Antibody in Western Blot (WB)
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FIGURE: 1 / 4

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JMJD2B Antibody (MA5-31784) in WB

Western blot analysis of JMJD2B in HEK293 (1) and KDM4B cell lysate. Samples were incubated with JMJD2B monoclonal antibody (Product # MA5-31784) using a dilution of 1:500-1:2000. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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JMJD2B Antibody in Western Blot (WB)
JMJD2B Antibody in Western Blot (WB)
JMJD2B Antibody in Flow Cytometry (Flow)
JMJD2B Antibody in ELISA (ELISA)
JMJD2B Monoclonal Antibody (3A6H6)

Product Details

MA5-31784

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Flow Cytometry (Flow)

1:200-1:400
-

ELISA (ELISA)

1:10,000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

3A6H6

Immunogen

Purified recombinant fragment of human KDM4B (AA: 960-1096) expressed in E. coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2787407

Product Specific Information

MA5-31784 has been tested in indirect ELISA.

Target Information

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: [histone H3]-trimethyl-L-lysine(9) demethylase 4B; JmjC domain-containing histone demethylation protein 3B; jumonji domain containing 2B; Jumonji domain-containing protein 2B; lysine (K)-specific demethylase 4B; Lysine-specific demethylase 4B; tudor domain containing 14B

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Gene Aliases: 4732474L06Rik; JHDM3B; JMJD2B; KDM4B; KIAA0876; mKIAA0876; TDRD14B

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UniProt ID: (Human) O94953, (Mouse) Q91VY5

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Entrez Gene ID: (Human) 23030, (Mouse) 193796

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Function(s)
zinc ion binding histone demethylase activity dioxygenase activity sulfonate dioxygenase activity oxidoreductase activity 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity procollagen-proline dioxygenase activity hypophosphite dioxygenase activity DNA-N1-methyladenine dioxygenase activity metal ion binding C-19 gibberellin 2-beta-dioxygenase activity C-20 gibberellin 2-beta-dioxygenase activity
Process(es)
transcription, DNA-templated regulation of transcription, DNA-templated histone demethylation oxidation-reduction process chromatin modification
It has to be done as per old AB suggested Products section.
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