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  • JMJD2A Antibodies

Invitrogen

JMJD2A Polyclonal Antibody

View all (20) JMJD2A antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite JMJD2A Polyclonal Antibody

  • Antibody Testing Data (8)
JMJD2A Antibody in Immunocytochemistry (ICC/IF)
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JMJD2A Antibody in Immunocytochemistry (ICC/IF)
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JMJD2A Antibody (PA5-119262) in ICC/IF

Immunocytochemistry analysis of JMJD2A in Human MCF7 cells using JMJD2A Polyclonal Antibody (Product # PA5-119262) at a dilution of 20 µg/mL, followed by secondary antibody staining with 1 µg/mL FITC-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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JMJD2A Antibody in Immunocytochemistry (ICC/IF)
JMJD2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
JMJD2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
JMJD2A Antibody in Western Blot (WB)
JMJD2A Antibody in Western Blot (WB)
JMJD2A Antibody in Western Blot (WB)
JMJD2A Antibody in Western Blot (WB)
JMJD2A Antibody in Western Blot (WB)
JMJD2A Polyclonal Antibody

Product Details

PA5-119262

Applications
Tested Dilution
Publications

Western Blot (WB)

0.01-2 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

5-20 µg/mL
-

Immunocytochemistry (ICC/IF)

5-20 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein Lysine Specific Demethylase 4A. The antigen corresponds to amino acid range 141-310 of the target protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2903760

Target Information

JMJD2A is a member of the Jumonji domain 2 (JMJD2) family and a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: [histone H3]-trimethyl-L-lysine(36) demethylase 4A; [histone H3]-trimethyl-L-lysine(9) demethylase 4A; JmjC domain-containing histone demethylation protein 3A; jumonji C domain-containing histone demethylase 3A; jumonji domain containing 2; jumonji domain containing 2A; Jumonji domain-containing protein 2A; lysine (K)-specific demethylase 4A; Lysine-specific demethylase 4A; tudor domain containing 14A

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Gene Aliases: D4Ertd222e; JHDM3A; JMJD2; JMJD2A; KDM4A; KIAA0677; mKIAA0677; TDRD14A

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UniProt ID: (Human) O75164, (Mouse) Q8BW72

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Entrez Gene ID: (Human) 9682, (Mouse) 230674

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Function(s)
protein binding zinc ion binding ubiquitin protein ligase binding histone demethylase activity methylated histone binding histone demethylase activity (H3-K36 specific) sulfonate dioxygenase activity double-stranded DNA binding oxidoreductase activity 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity procollagen-proline dioxygenase activity hypophosphite dioxygenase activity DNA-N1-methyladenine dioxygenase activity metal ion binding dioxygenase activity C-19 gibberellin 2-beta-dioxygenase activity C-20 gibberellin 2-beta-dioxygenase activity
Process(es)
transcription, DNA-templated negative regulation of autophagy negative regulation of gene expression cardiac muscle hypertrophy in response to stress viral process histone demethylation negative regulation of transcription, DNA-templated oxidation-reduction process histone H3-K36 demethylation negative regulation of histone H3-K9 trimethylation regulation of transcription, DNA-templated positive regulation of gene expression chromatin modification positive regulation of neuron differentiation negative regulation of astrocyte differentiation negative regulation of cell death
It has to be done as per old AB suggested Products section.
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