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OriGene
IL34 Monoclonal Antibody (OTI5E1), TrueMAB™
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FIGURE: 1 / 9
IL34 Antibody (CF811737) in IHC (P)
Product Details
CF811737
Species Reactivity
Host/Isotype
Class
Type
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Immunogen
Conjugate
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Purification
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Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: IL-34; ILN; Interleukin; Interleukin-34; Interleukin34
Gene Aliases: C16orf77; IL-34; IL34
UniProt ID: (Human) Q6ZMJ4
Entrez Gene ID: (Human) 146433
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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