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  • Primary Antibodies ›
  • IL1RA Antibodies

Invitrogen

IL1RA Polyclonal Antibody

View all (52) IL1RA antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite IL1RA Polyclonal Antibody

  • Antibody Testing Data (4)
IL1RA Antibody in Immunocytochemistry (ICC/IF)
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IL1RA Antibody in Immunocytochemistry (ICC/IF)
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IL1RA Antibody (PA5-96052) in ICC/IF

Immunofluorescence analysis of IL1RA in HepG2 cells. Samples were incubated with IL1RA Polyclonal antibody (Product # PA5-96052) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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IL1RA Antibody in Immunocytochemistry (ICC/IF)
IL1RA Antibody in Immunocytochemistry (ICC/IF)
IL1RA Antibody in Immunohistochemistry (Paraffin) (IHC (P))
IL1RA Antibody in Western Blot (WB)
IL1RA Polyclonal Antibody

Product Details

PA5-96052

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 24-177 of human IL1RA (NP_7762141)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.23 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2807854

Product Specific Information

Positive Samples: 293T, HeLa, NIH/3T3, HL-60, BT-474, HT-29; Cellular Location: Cytoplasm

Immunogen sequence: ICRPSGRKSS KMQAFRIWDV NQKTFYLRNN QLVAGYLQGP NVNLEEKIDV VPIEPHALFL GIHGGKMCLS CVKSGDETRL QLEAVNITDL SENRKQDKRF AFIRSDSGPT TSFESAACPG WFLCTAMEAD QPVSLTNMPD EGVMVTKFYF QEDE

Target Information

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD121A; D2S1473; ICIL-1RA; IL 1 receptor antagonist; il-1 receptor; il-1r; IL-1R-alpha; IL-1RN; IL1 inhibitor; il1 receptor; IL1 receptor antagonist; IL1-RA; IL1R; IL1RN (IL1F3); interleukin-1 receptor; Interleukin-1 receptor antagonist protein; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); IRAP; MGC10430; P80; type II interleukin-1 receptor antagonist

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Gene Aliases: DIRA; F630041P17Rik; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IL1RN; IRAP; MVCD4

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UniProt ID: (Human) P18510, (Mouse) P25085, (Rat) P25086

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Entrez Gene ID: (Human) 3557, (Mouse) 16181, (Rat) 60582

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Function(s)
cytokine activity interleukin-1, Type I receptor binding interleukin-1, Type II receptor binding interleukin-1 receptor antagonist activity protein binding interleukin-1 Type I receptor antagonist activity interleukin-1 Type II receptor antagonist activity interleukin-1 receptor binding
Process(es)
fever generation negative regulation of cytokine-mediated signaling pathway lipid metabolic process acute-phase response memory negative regulation of glutamate secretion cytokine-mediated signaling pathway sensory perception of pain insulin secretion negative regulation of cell migration negative regulation of heterotypic cell-cell adhesion negative regulation of apoptotic process positive regulation of JUN kinase activity negative regulation of membrane potential response to glucocorticoid extracellular negative regulation of signal transduction negative regulation of receptor activity negative regulation of interleukin-1-mediated signaling pathway immune response chronic inflammatory response to antigenic stimulus female pregnancy negative regulation of signal transduction response to organonitrogen compound response to organic cyclic compound response to activity carboxylic acid metabolic process response to lipopolysaccharide response to drug response to starvation response to interleukin-1 response to interleukin-4 cellular response to norepinephrine stimulus
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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