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Bioss
IFNAR2 Polyclonal Antibody
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Product Details
BS-7022R
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Target Information
The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: human interferon alpha/beta receptor; IFN alpha/betaRbeta; IFN R2; IFN-alpha/beta receptor 2; IFN-alpha/betaR2; IFN-alpha/betaRbeta; IFN-R-2; IFNalpha/beta R2; IFNalpha/beta-Rbeta; IFNalpha/betaR2; IFNR2; interferon (alpha, beta and omega) receptor 2; Interferon alpha binding protein; Interferon alpha/beta receptor 2; interferon receptor 2c; interferon-alpha/beta receptor 2; interferon-alpha/beta receptor beta chain; type I interferon alpha/beta receptor 2a; Type I interferon receptor 2
Gene Aliases: AI747302; IFN-alpha-REC; IFN-R; IFNABR; Ifnar-2; IFNAR2; IFNARB; IMD45
UniProt ID: (Human) P48551, (Mouse) O35664
Entrez Gene ID: (Human) 3455, (Mouse) 15976, (Rat) 686326
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