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Invitrogen
ID4 Polyclonal Antibody
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FIGURE: 1 / 2
ID4 Antibody (PA5-40522) in WB
Product Details
PA5-40522
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Storage buffer
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RRID
Product Specific Information
Peptide sequence: CYSRLRRLVP TIPPNKKVSK VEILQHVIDY ILDLQLALET HPALLRQPPP
Sequence homology: Cow: 85%; Dog: 100%; Guinea Pig: 85%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 79%; Rat: 100%; Zebrafish: 86%
Target Information
ID4 is transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: bHLHb27; Class B basic helix-loop-helix protein 27; DNA-binding protein inhibitor ID-4; Inhibitor of differentiation 4; Inhibitor of DNA binding 4; inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
Gene Aliases: BHLHB27; ID4; IDB4
UniProt ID: (Human) P47928
Entrez Gene ID: (Human) 3400
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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