Disclaimer

Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

  • Primary Antibodies ›
  • ICOS (CD278) Antibodies

Invitrogen

ICOS (CD278) Polyclonal Antibody

View all (88) ICOS (CD278) antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ICOS (CD278) Polyclonal Antibody

  • Antibody Testing Data (4)
ICOS (CD278) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.
ICOS (CD278) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.

FIGURE: 1 / 4

{{ $ctrl.currentElement.advancedVerification.fullName }}
{{ $ctrl.currentElement.advancedVerification.text }}

ICOS (CD278) Antibody (PA5-79432) in IHC (P)

Immunohistochemistry analysis of ICOS (CD278) on paraffin-embedded mouse thymus tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with ICOS (CD278) polyclonal antibody (Product# PA5-79432) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-rabbit IgG (30 minutes at ... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
Published figure supplied by benchsci-logo
PMID: {{$ctrl.currentElement.benchSciPubmedId}}
View Product

{{$ctrl.videoDesc}}

{{$ctrl.videoLongDesc}}

ICOS (CD278) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ICOS (CD278) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ICOS (CD278) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ICOS (CD278) Antibody in Western Blot (WB)
ICOS (CD278) Polyclonal Antibody

Product Details

PA5-79432

Applications
Tested Dilution
Publications

Western Blot (WB)

0.1-0.5 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

0.5-1 µg/mL
-

ELISA (ELISA)

0.1-0.5 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

E. coli-derived mouse ICOS recombinant protein (Position: E21-S200).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

500 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 4mg trehalose

Contains

0.05mg sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2746548

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Positive Control - WB: mouse stomach tissue, mouse spleen tissue, mouse thymus tissue, mouse small intestine tissue, rat thymus tissue, human placenta tissue. IHC: mouse spleen tissue, mouse thymus tissue, rat spleen tissue.

Target Information

ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation. ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: Activation-inducible lymphocyte immunomediatory molecule; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; inducible costimulator; inducible T-cell co-stimulator; Inducible T-cell costimulator

View more View less

Gene Aliases: AILIM; CCLP; CD278; CRP-1; CVID1; H4; ICOS; Ly115

View more View less

UniProt ID: (Human) Q9Y6W8, (Rat) Q9R1T7, (Mouse) Q9WVS0

View more View less

Entrez Gene ID: (Human) 29851, (Rat) 64545, (Mouse) 54167

View more View less

Function(s)
molecular_function protein binding
Process(es)
T cell tolerance induction single organismal cell-cell adhesion T cell costimulation immune response
It has to be done as per old AB suggested Products section.
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support

Your items have has been added!


Host server : magellan-search-649bfd9c6b-jlsz7:80/100.66.128.142:80.
git-commit: 6001d82975f0049f9efc09ec70b1b2d89229eeb3
git-url: https://github.com/thermofisher/magellan-search
git-branch: release/2.36.2-2025.09.39-1.0