Invitrogen

HuR Monoclonal Antibody (OTI14F4)

Name: HuR Monoclonal Antibody (OTI14F4)
Brand: Invitrogen
SKU: MA5-25037

View all (27) HuR antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (8)

HuR Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 8

HuR Antibody (MA5-25037) in IHC (P)

Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of breast tissue. To expose target proteins, 10mM citric buffer, pH6.0, 100°C for 10min was used. Following antigen retrieval, tissues were probed with a ELAVL1 monoclonal antibody (Product # MA5-25037) at a dilution of 1:50.

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Immunogen image

Immunogen Image HuR Monoclonal Antibody (OTI14F4)

Product Details

MA5-25037

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

Immunohistochemistry (Paraffin) (IHC (P))

1:50

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI14F4

Immunogen

Full length human recombinant protein of ELAVL1 produced in HEK293T cell

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.78 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2723254

Target Information

The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); ELAV-like protein 1; embryonic lethal, abnormal vision, drosophila, homolog-like 1; Hu antigen R; Hu-antigen R; Human antigen R; HuR

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Gene Aliases: ELAV1; ELAVL1; Hua; HUR; MelG

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UniProt ID: (Human) Q15717

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Entrez Gene ID: (Human) 1994

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Function(s)

nucleotide binding RNA binding double-stranded RNA binding mRNA binding mRNA 3'-UTR binding protein binding AU-rich element binding protein kinase binding mRNA 3'-UTR AU-rich region binding protein homodimerization activity poly(A) RNA binding

Process(es)

mRNA splicing, via spliceosome multicellular organism development regulation of mRNA stability positive regulation of translation mRNA stabilization negative regulation of gene silencing by miRNA 3'-UTR-mediated mRNA stabilization regulation of stem cell population maintenance

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HuR Monoclonal Antibody (OTI14F4)

HuR Antibody (MA5-25037) in IHC (P)

Product Details

MA5-25037

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

References (0)

Bioinformatics

Performance Guarantee

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