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Invitrogen
HSP60 Monoclonal Antibody (A57-E4)
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Product Details
MA3-022
Species Reactivity
Published species
Host/Isotype
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Clone
Immunogen
Conjugate
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Product Specific Information
MA3-022 detects heat shock protein 60 kDa (HSP60) from bacteria. This antibody detects HSP60 from all three species of Chlamydia, Escherichia coli (GroEL), Salmonella typhimurium, Neisseria gonorrhoeae and Coxiella burnetti. MA3-022 does not cross react with HeLa cell HSP60.
MA3-022 has been successfully used in Western blot procedures. By Western blot, this antibody detects a single ~60 kDa protein representing HSP60 from C. trachomatis lysate.
The MA3-022 immunogen is recombinant Chlamydia trachomatis HSP60. Epitope mapping studies suggest that this antibody binds to a linear sequence of 6 amino acids of Chlamydia HSP60 amino acids 117-122.
Target Information
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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