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  • Primary Antibodies ›
  • HOXA5 Antibodies

Abnova

HOXA5 Monoclonal Antibody (4E12)

View all (30) HOXA5 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite HOXA5 Monoclonal Antibody (4E12)

HOXA5 Monoclonal Antibody (4E12)

Product Details

H00003202-M14

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

ELISA (ELISA)

10 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

4E12

Immunogen

HOXA5 (NP_061975, 91 a.a. approximately 200 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: TSTHSPQPDP LPCSAVAPSP GSDSHHGGKN SLSNSSGASA DAGSTHISSR EGVGTASGAE EDAPASSEQA SAQSEPSPAP PAQPQIYPWM RKLHISHDNI GGPEGKRART *

Target Information

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: homeo box 1C; homeo box A5; Homeobox protein Hox-1C; Homeobox protein Hox-A5; homeobox protein HOXA5; Hox-1C

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Gene Aliases: HOX1; HOX1.3; HOX1C; HOXA5

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UniProt ID: (Human) P20719

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Entrez Gene ID: (Human) 3202

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Function(s)
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding
Process(es)
respiratory system process transcription from RNA polymerase II promoter anterior/posterior pattern specification positive regulation of receptor biosynthetic process cell migration negative regulation of angiogenesis thyroid gland development regulation of mammary gland epithelial cell proliferation multicellular organism growth positive regulation of apoptotic process positive regulation of myeloid cell differentiation negative regulation of erythrocyte differentiation positive regulation of transcription from RNA polymerase II promoter lung alveolus development embryonic skeletal system morphogenesis bronchiole development epithelial tube branching involved in lung morphogenesis lung goblet cell differentiation lung-associated mesenchyme development trachea cartilage morphogenesis intestinal epithelial cell maturation mesenchymal-epithelial cell signaling mammary gland epithelial cell differentiation mammary gland alveolus development cell-cell signaling involved in mammary gland development
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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