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HOXA5 Polyclonal Antibody

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers
HOXA5 Polyclonal Antibody

Product Details

BS-5713R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human HOXA5, amino acids 201-270.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: homeo box 1C; homeo box A5; Homeobox protein Hox-1.3; Homeobox protein Hox-1C; Homeobox protein Hox-A5; homeobox protein HOXA5; Homeobox protein M2; hox-1.3; Hox-1C

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Gene Aliases: Hox-1.3; HOX1; HOX1.3; HOX1C; Hoxa-5; HOXA5

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UniProt ID: (Human) P20719, (Mouse) P09021

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Entrez Gene ID: (Human) 3202, (Rat) 79241, (Mouse) 15402

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Function(s)
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding molecular_function sequence-specific DNA binding
Process(es)
skeletal system development morphogenesis of an epithelium respiratory system process transcription, DNA-templated regulation of transcription, DNA-templated multicellular organism development pattern specification process respiratory gaseous exchange anterior/posterior pattern specification positive regulation of receptor biosynthetic process cell migration negative regulation of angiogenesis lung development thyroid gland development regulation of mammary gland epithelial cell proliferation multicellular organism growth positive regulation of apoptotic process positive regulation of myeloid cell differentiation negative regulation of erythrocyte differentiation positive regulation of transcription from RNA polymerase II promoter lung alveolus development embryonic skeletal system morphogenesis embryonic skeletal system development bronchiole development trachea morphogenesis epithelial tube branching involved in lung morphogenesis lung goblet cell differentiation lobar bronchus epithelium development lung-associated mesenchyme development trachea cartilage morphogenesis cartilage morphogenesis intestinal epithelial cell maturation mesenchymal-epithelial cell signaling mammary gland epithelial cell differentiation mammary gland alveolus development cell-cell signaling involved in mammary gland development transcription from RNA polymerase II promoter
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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