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  • HK3 Antibodies

Proteintech

HK3 Polyclonal Antibody

8 References
View all (9) HK3 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite HK3 Polyclonal Antibody

  • Antibody Testing Data (2)
HK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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HK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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HK3 Antibody (13333-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human lung cancer using 13333-1-AP (HK3 antibody) at dilution of 1:100 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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HK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
HK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
HK3 Polyclonal Antibody

Product Details

13333-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

-
View 3 publications 3 publications

Immunohistochemistry (IHC)

-
View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Not applicable (N/A)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

HK3 Fusion Protein Ag4148 (622-923 aa encoded by BC028129)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.19 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: LLNWTKGFK ASDCEGQDVV SLLREAITRR QAVELNVVAI VNDTVGTMMS CGYEDPRCEI GLIVGTGTNA CYMEELRNVA GVPGDSGRMC INMEWGAFGD DGSLAMLSTR FDASVDQASI NPGKQRFEKM ISGMYLGEIV RHILLHLTSL GVLFRGQQIQ RLQTRDIFKT KFLSEIESDS LALRQVRAIL EDLGLPLTSD DALMVLEVCQ AVSQRAAQLC GAGVAAVVEK IRENRGLEEL AVSVGVDGTL YKLHPRFSSL VAATVRELAP RCVVTFLQSE DGSGKGAALV TAVACRLAQL TRV (622-923 aa encoded by BC028129)

Target Information

Hexokinases phosphorylate glucose to produce glucose 6 phosphate, thus committing glucose to the glycolytic pathway. In vertebrates there are four major glucose phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). Similar to hexokinases I and II, the allosteric enzyme hexokinase III is inhibited by its product glucose 6 phosphate. The catalytic activity of hexokinase III is associated with the C terminus while regulatory function is associated with the N terminus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: ATP:D-hexose 6-phosphotransferase; hexokinase 3 (white cell); hexokinase iii; Hexokinase type III; Hexokinase-3; Hexokinase-C; Hexokinase3; HK III

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Gene Aliases: HK III; HK-III; HK3; HKIII; HXK3; RNU73859

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UniProt ID: (Human) P52790, (Rat) P27926, (Mouse) Q3TRM8

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Entrez Gene ID: (Human) 3101, (Rat) 25060, (Mouse) 212032

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Function(s)
glucokinase activity hexokinase activity ATP binding glucose binding fructokinase activity mannokinase activity protein binding enzyme binding hormone binding nucleotide binding catalytic activity kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor
Process(es)
cellular glucose homeostasis glycolytic process biological_process hexose metabolic process carbohydrate phosphorylation glucose 6-phosphate metabolic process carbohydrate metabolic process metabolic process phosphorylation negative regulation of hydrogen peroxide-mediated programmed cell death glucose transport canonical glycolysis
It has to be done as per old AB suggested Products section.
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