HES1 Recombinant Rabbit Monoclonal Antibody (SC06-21)

transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein homodimerization activity histone deacetylase binding sequence-specific DNA binding chaperone binding N-box binding RNA polymerase II transcription factor activity, sequence-specific DNA binding chromatin binding JUN kinase binding protein complex binding protein dimerization activity E-box binding

negative regulation of transcription from RNA polymerase II promoter liver development embryonic heart tube morphogenesis outflow tract morphogenesis regulation of secondary heart field cardioblast proliferation ventricular septum development transcription, DNA-templated protein complex assembly cell adhesion Notch signaling pathway smoothened signaling pathway STAT protein import into nucleus nervous system development positive regulation of cell proliferation cell migration telencephalon development midbrain-hindbrain boundary morphogenesis oculomotor nerve development trochlear nerve development hindbrain morphogenesis forebrain radial glial cell differentiation adenohypophysis development lung development positive regulation of BMP signaling pathway midbrain development pancreas development somatic stem cell population maintenance ascending aorta morphogenesis positive regulation of T cell proliferation positive regulation of tyrosine phosphorylation of Stat3 protein auditory receptor cell fate determination positive regulation of DNA binding regulation of fat cell differentiation negative regulation of auditory receptor cell differentiation positive regulation of Notch signaling pathway negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of mitotic cell cycle, embryonic lateral inhibition positive regulation of JAK-STAT cascade cell maturation thymus development cell morphogenesis involved in neuron differentiation positive regulation of astrocyte differentiation negative regulation of oligodendrocyte differentiation artery morphogenesis regulation of epithelial cell proliferation inner ear receptor stereocilium organization regulation of timing of neuron differentiation negative regulation of glial cell proliferation ventricular septum morphogenesis ureteric bud morphogenesis labyrinthine layer blood vessel development common bile duct development negative regulation of stomach neuroendocrine cell differentiation cardiac neural crest cell development involved in outflow tract morphogenesis pharyngeal arch artery morphogenesis glomerulus vasculature development comma-shaped body morphogenesis S-shaped body morphogenesis renal interstitial fibroblast development metanephric nephron tubule morphogenesis cochlea development establishment of epithelial cell polarity vascular smooth muscle cell development neuronal stem cell population maintenance positive regulation of protein targeting to mitochondrion negative regulation of pancreatic A cell differentiation negative regulation of stem cell differentiation negative regulation of pro-B cell differentiation negative regulation of forebrain neuron differentiation in utero embryonic development regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter pattern specification process positive regulation of gene expression negative regulation of gene expression negative regulation of neuron projection development neural tube development pituitary gland development hair cell differentiation aorta morphogenesis auditory receptor cell differentiation regulation of protein heterodimerization activity cell fate commitment negative regulation of cell differentiation negative regulation of neuron differentiation positive regulation of glial cell differentiation positive regulation of transcription, DNA-templated regulation of timing of cell differentiation regulation of neurogenesis negative regulation of neurogenesis negative regulation of calcium ion import negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding cellular response to nerve growth factor stimulus negative regulation of inner ear receptor cell differentiation response to organic cyclic compound neuron differentiation response to alkaloid cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to fatty acid response to thyroid hormone