Disclaimer

Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

  • Primary Antibodies ›
  • H2BK5ac Antibodies

Invitrogen

H2BK5ac Polyclonal Antibody

View all (6) H2BK5ac antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite H2BK5ac Polyclonal Antibody

  • Antibody Testing Data (7)
H2BK5ac Antibody in Immunocytochemistry (ICC/IF)
Group 53 Created with Sketch.
H2BK5ac Antibody in Immunocytochemistry (ICC/IF)
Group 53 Created with Sketch.

FIGURE: 1 / 7

{{ $ctrl.currentElement.advancedVerification.fullName }}
{{ $ctrl.currentElement.advancedVerification.text }}

H2BK5ac Antibody (PA5-114691) in ICC/IF

Immunocytochemistry analysis of H2BK5ac in HepG2 cells (4hrs of LPS treatment). Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114691) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
Published figure supplied by benchsci-logo
PMID: {{$ctrl.currentElement.benchSciPubmedId}}
View Product

{{$ctrl.videoDesc}}

{{$ctrl.videoLongDesc}}

H2BK5ac Antibody in Immunocytochemistry (ICC/IF)
H2BK5ac Antibody in Immunohistochemistry (Paraffin) (IHC (P))
H2BK5ac Antibody in Immunohistochemistry (Paraffin) (IHC (P))
H2BK5ac Antibody in Immunohistochemistry (Paraffin) (IHC (P))
H2BK5ac Antibody in Immunohistochemistry (Paraffin) (IHC (P))
H2BK5ac Antibody in Western Blot (WB)
H2BK5ac Antibody in Western Blot (WB)
H2BK5ac Polyclonal Antibody

Product Details

PA5-114691

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human H2BFS(Accession P57053), corresponding to amino acid residues M1-G27.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2899327

Product Specific Information

Antibody detects endogenous levels of Acetyl-H2B only when acetylated at Lys5.

Target Information

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: Acetyl-Histone H2; Acetyl-Histone H2B K5; Acetyl-Histone H2B Lys5; H2B 291A; H2B 291B; H2b 613; H2B GL105; H2B histone family member W testis-specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member M; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member S; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B histone family, member W, testis-specific; H2B K; H2B type 12; h2B-143; h2B-221; H2B-clustered histone 17; H2B-clustered histone 18; H2B-clustered histone 21; H2B-clustered histone 26; H2B-clustered histone 3; H2B-clustered histone 5; H2B-clustered histone 9; H2B.U histone 1; H2B.W histone 1; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/q; H2B/r; H2B/s; H2BK12ac; H2BK15ac; H2BK5ac; H2BLys5ac; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRA-interacting protein 2; HIST1H3I; histone 1, H2ba; histone 1, H2bb; histone 1, H2bc; histone 1, H2bd; histone 1, H2bg; histone 1, H2bh; histone 1, H2bi; histone 1, H2bj; histone 1, H2bk; histone 1, H2bl; histone 1, H2bm; histone 1, H2bn; histone 1, H2bo; histone 2, H2be; Histone 2B; histone 3, H2bb; histone cluster 1, H2bc; histone cluster 1, H2bd; histone cluster 1, H2bm; histone cluster 1, H2bn; histone cluster 1, H2bo; histone cluster 3, H2bb; histone family member; histone H2B; Histone H2B type 1-A; Histone H2B type 1-B; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-C/E/G; Histone H2B type 1-D; Histone H2B type 1-F/J/L; Histone H2B type 1-H; Histone H2B type 1-J; Histone H2B type 1-K; Histone H2B type 1-L; Histone H2B type 1-M; Histone H2B type 1-N; Histone H2B type 1-O; Histone H2B type 2-E; Histone H2B type 2-F; Histone H2B type 3-B; Histone H2B type F-M; histone H2B type F-S-like; Histone H2B type W-T; Histone H2B, testis; Histone H2B-GL105; Histone H2B.1; Histone H2B.1 A; Histone H2B.1 B; Histone H2B.2; Histone H2B.a; Histone H2B.b; Histone H2B.c; Histone H2B.d; Histone H2B.e; Histone H2B.f; Histone H2B.g; Histone H2B.h; Histone H2B.I; Histone H2B.j; Histone H2B.k; Histone H2B.l; Histone H2B.n; Histone H2B.q; Histone H2B.r; Histone H2B.s; MGC125414; MGC125415; MGC125416; MGC9388; RP1-193B12.10; testis-specific histone 2b; Testis-specific histone H2B; TSH2B.1

View more View less

Gene Aliases: 2610022J01Rik; AV127319; bA317E16.3; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; GL105; H2B; H2b-143; H2b-221; H2b-291b; H2b-613; H2b-f; H2b-j; H2b-l; H2b-n; H2B.1; H2B.1A; H2B.1B; H2B.2; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/j; H2B/k; H2B/l; H2B/n; H2B/r; H2B/S; H2Bb; H2BC1; H2BC10; H2BC11; H2BC12; H2BC13; H2BC14; H2BC15; H2BC17; H2BC18; H2BC21; H2BC26; H2BC3; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2BC9; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFQ; H2BFR; H2bfs; H2BFT; H2BFU; H2BFWT; H2BGL105; H2BJ; H2BK; H2BQ; H2BU1; H2BW1; H2BW2; HIRIP1; HIRIP2; HIST1H2BA; HIST1H2BB; HIST1H2BC; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BH; HIST1H2BI; HIST1H2BJ; HIST1H2BK; HIST1H2BL; HIST1H2BM; HIST1H2BN; HIST1H2BO; HIST2H2BE; HIST2H2BF; HIST3H2BB; R74621; STBP; T25626; TH2B; TH2B-175; TSH2B; TSH2B.1

View more View less

UniProt ID: (Human) P0C1H6, (Human) Q7Z2G1, (Human) Q96A08, (Human) P33778, (Human) P62807, (Human) Q93079, (Human) P06899, (Human) O60814, (Human) Q99880, (Human) Q99879, (Human) Q99877, (Human) P23527, (Human) Q16778, (Human) Q5QNW6, (Human) Q8N257, (Rat) Q00729, (Mouse) P70696, (Mouse) Q64475, (Mouse) Q6ZWY9, (Mouse) Q64478, (Mouse) P10853, (Mouse) Q8CGP1, (Mouse) P10854, (Mouse) Q64524

View more View less

Entrez Gene ID: (Human) 286436, (Human) 158983, (Human) 255626, (Human) 3018, (Human) 8347, (Human) 3017, (Human) 8339, (Human) 8345, (Human) 8346, (Human) 8970, (Human) 85236, (Human) 8340, (Human) 8342, (Human) 8341, (Human) 8348, (Human) 8349, (Human) 440689, (Human) 128312, (Rat) 24829, (Mouse) 319177, (Mouse) 319178, (Mouse) 68024, (Rat) 361247, (Mouse) 319181, (Mouse) 319182, (Mouse) 319183, (Mouse) 319184, (Rat) 680312, (Mouse) 319186, (Rat) 291157, (Mouse) 319190, (Rat) 691488, (Human) 102724334

View more View less

Function(s)
DNA binding protein heterodimerization activity molecular_function protein binding
Process(es)
nucleosome assembly innate immune response in mucosa antibacterial humoral response defense response to Gram-positive bacterium chromatin organization nucleosome disassembly inflammatory response plasminogen activation spermatogenesis, exchange of chromosomal proteins positive regulation of binding mononuclear cell migration biological_process cellular response to acid chemical
It has to be done as per old AB suggested Products section.
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support

Your items have has been added!


Host server : magellan-search-649bfd9c6b-jlsz7:80/100.66.128.142:80.
git-commit: 6001d82975f0049f9efc09ec70b1b2d89229eeb3
git-url: https://github.com/thermofisher/magellan-search
git-branch: release/2.36.2-2025.09.39-1.0