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  • Gelsolin Antibodies

Invitrogen

Gelsolin Polyclonal Antibody

View all (31) Gelsolin antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Gelsolin Polyclonal Antibody

  • Antibody Testing Data (1)
Gelsolin Antibody in Western Blot (WB)
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Gelsolin Antibody in Western Blot (WB)
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Gelsolin Antibody (PA5-142876) in WB

Western Blot analysis of Gelsolin in Human Duodenum lysate (35 µg protein in RIPA buffer) using Gelsolin Polyclonal Antibody (Product # PA5-142876) at 1 µg/mL incubated for 1 hour. Detected by chemiluminescence. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Gelsolin Antibody in Western Blot (WB)
Gelsolin Polyclonal Antibody

Product Details

PA5-142876

Applications
Tested Dilution
Publications

Western Blot (WB)

1-3 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide with sequence PQGRVPEARPNS-C.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2933519

Product Specific Information

Additional Information: This antibody is expected to recognize isoform a (NP_000168.1) only .

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.

Target Information

The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Actin-depolymerizing factor; ADF; ADFBrevin; AGEL; Brevin; DKFZp313L0718; Gelsolin; RP11-477J21.1

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Gene Aliases: ADF; AGEL; GSN

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UniProt ID: (Human) P06396

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Entrez Gene ID: (Human) 2934

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Function(s)
actin binding calcium ion binding protein binding protein domain specific binding myosin II binding
Process(es)
phagocytosis, engulfment aging positive regulation of gene expression oligodendrocyte development striated muscle atrophy extracellular matrix disassembly actin filament polymerization protein destabilization tissue regeneration sequestering of actin monomers cellular protein metabolic process actin nucleation response to ethanol negative regulation of viral entry into host cell phosphatidylinositol-mediated signaling actin filament severing barbed-end actin filament capping positive regulation of actin nucleation response to folic acid actin filament capping cilium morphogenesis cellular response to cadmium ion regulation of podosome assembly actin filament reorganization renal protein absorption hepatocyte apoptotic process positive regulation of keratinocyte apoptotic process regulation of wound healing, spreading of epidermal cells regulation of establishment of T cell polarity regulation of plasma membrane raft polarization regulation of receptor clustering positive regulation of protein processing in phagocytic vesicle amyloid fibril formation positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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