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  • Galectin 3 Antibodies

Proteintech

Galectin 3 Recombinant Rabbit Monoclonal Antibody (4M10)

View all (131) Galectin 3 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Galectin 3 Recombinant Rabbit Monoclonal Antibody (4M10)

Galectin 3 Recombinant Rabbit Monoclonal Antibody (4M10)
  • Antibody Testing Data (4)
Galectin 3 Antibody in Immunocytochemistry (ICC/IF)
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Galectin 3 Antibody in Immunocytochemistry (ICC/IF)
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Galectin 3 Antibody (82024-1-RR) in ICC/IF

Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using Galectin 3 antibody (82024-1-RR, Clone: 4M10 ) at dilution of 1:500 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Galectin 3 Antibody in Immunocytochemistry (ICC/IF)
Galectin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Galectin 3 Antibody in Western Blot (WB)
Galectin 3 Antibody in Immunoprecipitation (IP)

Product Details

82024-1-RR

Applications
Tested Dilution
Publications

Western Blot (WB)

1:5,000-1:50,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:250-1:1,000
-

Immunocytochemistry (ICC/IF)

1:250-1:1,000
-

ELISA (ELISA)

Assay-dependent
-

Immunoprecipitation (IP)

0.5-4 µg/1-3 mg of protein lysate
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

Mammalian cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

4M10

Immunogen

Recombinant protein
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated
  • CoraLite Plus 488
  • Request custom conjugation

Form

Liquid

Purification

Protein A

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: MADNFSLHDA LSGSGNPNPQ GWPGAWGNQP AGAGGYPGAS YPGAYPGQAP PGAYPGQAPP GAYPGAPGAY PGAPAPGVYP GPPSGPGAYP SSGQPSATGA YPATGPYGAP AGPLIVPYNL PLPGGVVPRM LITILGTVKP NANRIALDFQ RGNDVAFHFN PRFNENNRRV IVCNTKLDNN WGREERQSVF PFESGKPFKI QVLVEPDHFK VAVNDAHLLQ YNHRVKKLNE ISKLGISGDI DLTSASYTMI

Target Information

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 35 kDa lectin; advanced glycation end-product receptor 3; Carbohydrate-binding protein 35; CBP 35; CBP-30; Gal-3; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; Galectin-3; Galectin3; IgE-binding protein; L-29; L-31; L-34 galactoside-binding lectin; Laminin-binding protein; Lectin L-29; lectin, galactoside-binding, soluble, 3; MAC-2 antigen

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Gene Aliases: CBP35; GAL3; GALBP; GALIG; GBP; L-34; L31; LGALS2; LGALS3; Mac-2; MAC2

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UniProt ID: (Human) P17931

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Entrez Gene ID: (Human) 3958, (Mouse) 16854

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Function(s)
protein binding IgE binding carbohydrate binding chemoattractant activity laminin binding poly(A) RNA binding Fc-gamma receptor I complex binding monosaccharide binding disaccharide binding advanced glycation end-product receptor activity
Process(es)
monocyte chemotaxis mRNA processing RNA splicing neutrophil chemotaxis epithelial cell differentiation regulation of T cell proliferation innate immune response negative regulation of endocytosis eosinophil chemotaxis macrophage chemotaxis negative regulation of T cell receptor signaling pathway positive chemotaxis regulation of T cell apoptotic process mononuclear cell migration positive regulation of mononuclear cell migration positive regulation of calcium ion import regulation of extrinsic apoptotic signaling pathway via death domain receptors negative regulation of immunological synapse formation negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell positive regulation of dendritic cell differentiation negative regulation of extrinsic apoptotic signaling pathway skeletal system development immune system process signal transduction positive regulation of cell proliferation positive regulation of serotonin secretion cell differentiation extracellular matrix organization negative regulation of apoptotic process positive regulation of angiogenesis negative regulation of cell proliferation in bone marrow
It has to be done as per old AB suggested Products section.
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