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GSTM1 Monoclonal Antibody (3C5C2), CoraLite® Plus 488

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Cite GSTM1 Monoclonal Antibody (3C5C2), CoraLite® Plus 488

  • Antibody Testing Data (1)
GSTM1 Antibody in Flow Cytometry (Flow)
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GSTM1 Antibody in Flow Cytometry (Flow)
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GSTM1 Antibody (CL488-67862) in Flow

1X10^6 HeLa cells were intracellularly stained with 0.4 µg CoraLite® Plus 488 Anti-Human GSTM1 (CL488-67862, Clone:3C5C2) (red), or 0.4 µg Mouse IgG2b Isotype Control (CL488-66360-3, Clone: K11B8C4B5) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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GSTM1 Antibody in Flow Cytometry (Flow)
GSTM1 Monoclonal Antibody (3C5C2), CoraLite® Plus 488

Product Details

CL488-67862

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

0.4 µg/1x10^6 cell suspension
-
Product Specifications

Species Reactivity

Chicken, Human, Mouse, Pig, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

3C5C2

Immunogen

Recombinant protein
View immunogen

Conjugate

CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488
  • Unconjugated
  • Request custom conjugation

Excitation/Emission Max

493/522 nm

Form

Liquid

Purification

Protein A

Storage buffer

PBS with 50% glycerol, 0.5% BSA

Contains

0.05% ProClin 300

Storage conditions

-20°C, store in dark

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: MPMILGYWDI RGLAHAIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGAHKI TQSNAILCYI ARKHNLCGET EEEKIRVDIL ENQTMDNHMQ LGMICYNPEF EKLKPKYLEE LPEKLKLYSE FLGKRPWFAG NKGLEKISAY MKSSRFLPRP VFSKMAVWGN K

Target Information

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13. 3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; Glutathione S-transferase GT8.7; glutathione S-transferase M1; Glutathione S-transferase Mu 1; Glutathione S-transferase Yb-1; glutathione S-transferase Yb-1 subunit; glutathione-S-transferase mu type 1 (Yb1); glutathione-S-transferase, mu 1; glutathione-S-transferase, mu type 1 (Yb1); GST 1-1; GST 3-3; GST class-mu 1; GST HB subunit 4; GST Yb1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; HB subunit 4; pmGT10; S-(hydroxyalkyl)glutathione lyase

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Gene Aliases: GST1; GSTA3; Gstb-1; Gstb1; GSTM1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GTM1; H-B; MU; MU-1

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UniProt ID: (Human) P09488, (Mouse) P10649, (Rat) P04905

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Entrez Gene ID: (Human) 2944, (Mouse) 14862, (Rat) 24423

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Function(s)
glutathione transferase activity enzyme binding protein homodimerization activity glutathione binding steroid binding protein binding nickel cation binding transferase activity protein heterodimerization activity
Process(es)
glutathione metabolic process metabolic process cellular response to drug sensory perception of smell response to metal ion response to lithium ion response to lead ion nitrobenzene metabolic process xenobiotic catabolic process response to drug response to amino acid response to ethanol response to antibiotic response to axon injury cellular detoxification of nitrogen compound glutathione derivative biosynthetic process
It has to be done as per old AB suggested Products section.
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