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  • Gelsolin Antibodies

Abnova

GSN Monoclonal Antibody (3G5)

View all (31) Gelsolin antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite GSN Monoclonal Antibody (3G5)

  • Antibody Testing Data (5)
GSN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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GSN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 5

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GSN Antibody (H00002934-M01) in IHC (P)

Immunoperoxidase of monoclonal antibody to GSN on formalin-fixed paraffin-embedded human tonsil. Antibody concentration is 1 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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GSN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
GSN Antibody in Western Blot (WB)
GSN Antibody in Western Blot (WB)
GSN Antibody in Immunoprecipitation (IP)
GSN Antibody in ELISA (ELISA)
GSN Monoclonal Antibody (3G5)

Product Details

H00002934-M01

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

1 µg/mL
-

ELISA (ELISA)

0.03 ng/mL
-

Immunoprecipitation (IP)

1-5 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

3G5

Immunogen

GSN (AAH26033, 673 a.a. approximately 782 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: SNKIGRFVIE EVPGELMQED LATDDVMLLD TWDQVFVWVG KDSQEEEKTE ALTSAKRYIE TDPANRDRRT PITVVKQGFE PPSFVGWFLG WDDDYWSVDP LDRAMAELAA

Target Information

The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Actin-depolymerizing factor; ADF; ADFBrevin; AGEL; Brevin; DKFZp313L0718; Gelsolin; RP11-477J21.1

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Gene Aliases: ADF; AGEL; GSN

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UniProt ID: (Human) P06396

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Entrez Gene ID: (Human) 2934

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Function(s)
actin binding calcium ion binding protein binding protein domain specific binding myosin II binding
Process(es)
phagocytosis, engulfment aging positive regulation of gene expression oligodendrocyte development striated muscle atrophy extracellular matrix disassembly actin filament polymerization protein destabilization tissue regeneration sequestering of actin monomers cellular protein metabolic process actin nucleation response to ethanol negative regulation of viral entry into host cell phosphatidylinositol-mediated signaling actin filament severing barbed-end actin filament capping positive regulation of actin nucleation response to folic acid actin filament capping cilium morphogenesis cellular response to cadmium ion regulation of podosome assembly actin filament reorganization renal protein absorption hepatocyte apoptotic process positive regulation of keratinocyte apoptotic process regulation of wound healing, spreading of epidermal cells regulation of establishment of T cell polarity regulation of plasma membrane raft polarization regulation of receptor clustering positive regulation of protein processing in phagocytic vesicle amyloid fibril formation positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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