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  • Primary Antibodies ›
  • GRK6 Antibodies

Fabgennix

GRK6 Polyclonal Antibody, FITC

View all (21) GRK6 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite GRK6 Polyclonal Antibody, FITC

GRK6 Polyclonal Antibody, FITC

Product Details

GRK6-FITC

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide taken within amino acid region 500-550 on human G protein-coupled receptor kinase 6 protein.
View immunogen

Conjugate

FITC FITC FITC

Excitation/Emission Max

498/517 nm View spectra spectra

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

GRK6 is a member of the guanine nucleotide-binding protein coupled receptor kinase subfamily of the serine/threonine protein kinase family. GRK6 phosphorylates the activated forms of G protein-coupled receptors to initiate their deactivation. Several transcript variants encoding different isoforms have been described for GRK6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: EC 2.7.11.16; G protein-coupled receptor kinase 6; G protein-coupled receptor kinase GRK6; G-protein coupled receptor kinase 6; kinase GRK6

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Gene Aliases: GPRK6; GRK6

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UniProt ID: (Human) P43250, (Mouse) O70293

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Entrez Gene ID: (Human) 2870, (Mouse) 26385, (Rat) 59076

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Function(s)
G-protein coupled receptor kinase activity protein binding ATP binding beta-adrenergic receptor kinase activity nucleotide binding protein kinase activity protein serine/threonine kinase activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups
Process(es)
desensitization of G-protein coupled receptor protein signaling pathway protein phosphorylation regulation of G-protein coupled receptor protein signaling pathway negative regulation of anion channel activity Wnt signaling pathway signal transduction phosphorylation termination of G-protein coupled receptor signaling pathway
It has to be done as per old AB suggested Products section.
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