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Alomone Labs, LTD
GPR68 (OGR1) (extracellular) Polyclonal Antibody
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FIGURE: 1 / 3
GPR68 (OGR1) (extracellular) Antibody (AGR-042-200UL) in WB
Product Details
AGR-042-200UL
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
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Shipping conditions
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
GPR68 (also known as OGR1 - ovarian cancer G-protein coupled receptor 1) is a proton-sensing receptor involved in pH homeostasis. It represents an osteoblastic pH sensor regulating the cell-mediated response to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulate inositol phosphate (IP) production or CA2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Also found to serve as a tumor suppressor in prostate cancer. Mutations to the gene result in amelogenesis imperfecta, hypomaturation type 2A6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Brgr1; Brgrb; G-protein coupled receptor 12A; G-protein coupled receptor 68; GPR12A; OGR-1; ovarian cancer G protein-coupled receptor, 1; Ovarian cancer G-protein coupled receptor 1; Ovarian cancer G-protein coupled receptor 1 homolog; sphingosylphosphorylcholine receptor
Gene Aliases: BB131428; GPR12A; GPR68; OGR1
UniProt ID: (Human) Q15743, (Mouse) Q8BFQ3
Entrez Gene ID: (Human) 8111, (Mouse) 238377, (Rat) 314386
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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