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  • GPR56 Antibodies

Invitrogen

GPR56 Polyclonal Antibody

View all (18) GPR56 antibodies

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Protocols
Questions & Answers

Cite GPR56 Polyclonal Antibody

  • Antibody Testing Data (7)
GPR56 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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GPR56 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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GPR56 Antibody (PA5-33738) in IHC (P)

Immunohistochemistry analysis of GPR56 in human Skin, Melanoma. Samples were incubated with GPR56 polyclonal antibody (Product # PA5-33738). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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GPR56 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
GPR56 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
GPR56 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
GPR56 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
GPR56 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
GPR56 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
GPR56 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

PA5-33738

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

2.5-5 µg/mL
-
Product Specifications

Species Reactivity

Human, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 19 amino acid peptide from 1st cytoplasmic domain of human GPR56.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2551109

Product Specific Information

This antibody is not recommended for use in ICC applications.

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%) Pig (95%) Bovine, Rabbit (89%).

Target Information

GPR56 is a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 7-transmembrane protein with no EGF-like N-terminal domains-1; Adhesion G-protein coupled receptor G1; Cyt28; DKFZp781L1398; G protein-coupled receptor 56; G-protein coupled receptor 56; testicular tissue protein Li 77

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Gene Aliases: ADGRG1; BFPP; BPPR; GPR56; TM7LN4; TM7XN1; UNQ540/PRO1083

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UniProt ID: (Human) Q9Y653

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Entrez Gene ID: (Human) 9289

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Function(s)
G-protein coupled receptor activity collagen binding heparin binding extracellular matrix binding
Process(es)
angiogenesis cell adhesion cell surface receptor signaling pathway G-protein coupled receptor signaling pathway Rho protein signal transduction cell-cell signaling brain development negative regulation of cell proliferation vascular endothelial growth factor production cell migration cerebral cortex regionalization cerebral cortex radial glia guided migration layer formation in cerebral cortex positive regulation of Rho protein signal transduction positive regulation of cell adhesion protein kinase C signaling positive regulation of neural precursor cell proliferation negative regulation of neuron migration
It has to be done as per old AB suggested Products section.
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